Results 21 to 30 of about 128,950 (259)
Ra-223 induces clustered DNA damage and inhibits cell survival in several prostate cancer cell lines
Translational Oncology, 2022 The bone-seeking radiopharmaceutical Xofigo (Radium-223 dichloride) has demonstrated both extended survival and palliative effects in treatment of bone metastases in prostate cancer.
Andris Abramenkovs +4 more
doaj +1 more source
Tataloka, 2013 The aim of this study are (1) to assess the damage of settlement due to lahar flood in study area, (2) to analyze the damage of settlement and (3) to analyze the allocated space of settlement development based on classification of damage settlement ...
Rosalina Kumalawati +4 more
doaj +1 more source
PLoS ONE, 2020 DNA repair requires reorganization of the local chromatin structure to facilitate access to and repair of the DNA. Studying DNA double-strand break (DSB) repair in specific chromatin domains has been aided by the use of sequence-specific endonucleases to
Nealia C M House +3 more
doaj +1 more source
Which DNA Damage is Likely to Be Relevant in Hormetic Responses?
Dose-Response, 2008 Working under the assumption that hormesis is triggered by specific types of DNA damage, this report focuses on the types of damage which form the signature of ionizing radiation.
William A. Bernhard +2 more
doaj +1 more source
Visualization of complex DNA damage along accelerated ions tracks
EPJ Web of Conferences, 2018 The most deleterious DNA lesions induced by ionizing radiation are clustered DNA double-strand breaks (DSB). Clustered or complex DNA damage is a combination of a few simple lesions (single-strand breaks, base damage etc.) within one or two DNA helix ...
Kulikova Elena +5 more
doaj +1 more source
Inventory of sparse forest populations using adaptive cluster sampling
Silva Fennica, 2006 In many studies, adaptive cluster sampling (ACS) proved to be a powerful tool for assessing rare clustered populations that are difficult to estimate by means of conventional sampling methods.
Talvitie, Mervi +2 more
doaj +1 more source
Cells, 2020 Approximately 3 × 1017 DNA damage events take place per hour in the human body. Within clustered DNA lesions, they pose a serious problem for repair proteins, especially for iron−sulfur glycosylases (MutyH), which can recognize them by the ...
Boleslaw T. Karwowski
doaj +1 more source
Biomolecules, 2023 Every 24 h, roughly 3 × 1017 incidences of DNA damage are generated in the human body as a result of intra- or extra-cellular factors. The structure of the formed lesions is identical to that formed during radio- or chemotherapy.
Boleslaw Karwowski
doaj +1 more source
The observed clustering of damaging extra-tropical cyclones in Europe [PDF]
Natural Hazards and Earth System Sciences, 2015 Abstract. The clustering of severe European windstorms on annual timescales has substantial impacts on the re/insurance industry. Management of the risk is impaired by large uncertainties in estimates of clustering from historical storm datasets typically covering the past few decades. The uncertainties are unusually large because clustering depends on
openaire +3 more sources
Simultaneous induction of dispersed and clustered DNA lesions compromises DNA damage response in human peripheral blood lymphocytes. [PDF]
PLoS ONE, 2018 Due to its ability to induce DNA damage in a space and time controlled manner, ionising radiation is a unique tool for studying the mechanisms of DNA repair. The biological effectiveness of ionising radiation is related to the ionisation density which is
Lei Cheng +6 more
doaj +1 more source