Results 81 to 90 of about 572 (99)

Regulation of mRNA Polyadenylation Governs Mammalian Body Plan Formation in Gastruloids

The development and patterning of the early embryo is an exquisitely complex process involving a wide array of signaling factors, and internal and external cues.
Taborsky, David
core  

Genetic ancestry concordant RNA splicing in prostate cancer involves oncogenic genes and associates with recurrence. [PDF]

NPJ Precis Oncol
Al Abo M, Foo WC, Howard LE, McGue S, Lacroix B, Kephart J, Clayton A, Thornburg B, Anand M, Rothberg MB, McCall SJ, Huang J, Esther TA, Moul JW, Ferrandino MN, Polascik TJ, Robertson CN, Inman BA, Armstrong AJ, Wu Y, Hyslop T, George DJ, Patierno SR, Freedman JA.   +23 more
europepmc   +1 more source

Auxin-induced depletion of human CCR4-NOT subunits reveals opposing functions of CNOT1 and CNOT4 in mRNA metabolism. [PDF]

J Biol Chem
Kulkarni S, Smith C, Akinniyi OT, Giardine BM, Keller CA, Arnaoutov A, Reese JC.   +6 more
europepmc   +1 more source

Pathophysiological and translational implications of the dysregulation of molecular machineries controlling RNA metabolism in thyrotropinomas. [PDF]

iScience
G-García ME, Flores-Martínez Á, Arroyo-Millán L, Venegas E, Diaz-Perdigones CM, Maraver S, Cano D, Arráez C, Arráez MA, Japón MA, Martínez-Fuentes AJ, Soto-Moreno A, Fuentes-Fayos AC, Herrera-Martínez AD, Luque RM.   +14 more
europepmc   +1 more source

UV-type specific alteration of miRNA expression and its association with tumor progression and metastasis in SCC cell lines. [PDF]

J Cancer Res Clin Oncol, 2020
Chen IP, Bender M, Spassova I, Henning S, Kubat L, Fan K, Degenhardt S, Mhamdi-Ghodbani M, Sriram A, Volkmer B, Boukamp P, Becker JC, Greinert R.   +12 more
europepmc   +1 more source

Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma. [PDF]

Nat Commun
Galvan B, Ongena L, Bruyr J, Fettweis G, Lucarelli E, Lavergne A, Mariavelle E, O'Grady TM, Hassoun ZEO, Claes M, Dubois L, Lee KAW, Kruys V, Gueydan C, Durand J, Hervouet E, Geyer FH, Banito A, Imle R, Mao L, Jayavelu AK, Grünewald TGP, Cidre-Aranaz F, Twizere JC, Dequiedt F.   +24 more
europepmc   +1 more source

Assessment of PARN, CNOT6, CNOT6-LIKE, CNOT7 and CNOT8 deadenylases action in RNA stability [PDF]

, 2017
Κουλτούκη, Αικατερίνη
core  

The CCR4-NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression. [PDF]

Nat Commun, 2020
Ito-Kureha T, Miyao T, Nishijima S, Suzuki T, Koizumi SI, Villar-Briones A, Takahashi A, Akiyama N, Morita M, Naguro I, Ishikawa H, Ichijo H, Akiyama T, Yamamoto T.   +13 more
europepmc   +1 more source

Regulators of interferon-responsive microglia uncovered by Genome-wide CRISPRi screening. [PDF]

NPJ Dement
McQuade A, Castillo VC, Hagan V, Liang W, Ta T, Mishra R, Teter O, Gomes L, Gonzalez B, Teyssier N, Leng K, Kampmann M.   +11 more
europepmc   +1 more source

CNOT7 facilitates radiation resistance in colorectal cancer through TRIM21/XRCC6-mediated non-homologous end joining repair. [PDF]

Cell Death Dis
Li Y, Cui L, Wang S, Zhao Q, Du F, Du S, Yu C, Xia M, Zhao S, Luan T, Liu Y, Cui B.   +11 more
europepmc   +1 more source