Post-transcriptional Regulation of Circadian Rhythm: Involvement of the CCR4-NOT Complex [PDF]
, 2019 Circadian clocks are an endogenous internal timekeeping mechanism that drive the rhythmic expression of genes, controlling the 24 hr oscillatory pattern in behavior and physiology.
Haytham Mohamed
core +1 more source
BESST: a novel LncRNA knockout strategy with less genome perturbance. [PDF]
Nucleic Acids Res, 2023 Zhang S +11 more
europepmc +1 more source
A polar mechanism coordinates different regions of alternative splicing within a single gene [PDF]
, 2005 Alternative splicing plays a key role in generating protein diversity. Transfections with minigenes revealed coordination between two distant, alternatively spliced exons in the same gene.
Baralle, F.E. +9 more
core
Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.
Mol Cell, 2023 Höpfler M +6 more
europepmc +2 more sources
Estudo das funções fisiológicas da LAP1 e dos mecanismos patológicos subjacentes às envelopatias nucleares associadas à LAP1 [PDF]
Lamina-associated polypeptide 1 (LAP1) is a ubiquitous type II transmembrane protein of the nuclear envelope (NE), whose biological functions remain ill-defined.
Pereira, Cátia Daniela Isaías
core
Regulation of eukaryotic mRNA deadenylation and degradation by the Ccr4-Not complex. [PDF]
Front Cell Dev Biol, 2023 Pavanello L, Hall M, Winkler GS.
europepmc +1 more source
Poly(A) tail regulation in stem cells and early development. [PDF]
Cell RegenMiao X, Hu G.
europepmc +1 more source
A next-generation dual guide CRISPR system for genetic interaction library screening. [PDF]
Nat CommunBurgold T +12 more
europepmc +1 more source
The CCR4-NOT complex: a multifaceted sensor of molecular signals instructing eukaryotic mRNA translation and stability. [PDF]
Nucleic Acids ResCaulier G +4 more
europepmc +1 more source
Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome. [PDF]
RNA, 2021 Enwerem III +9 more
europepmc +1 more source