Molecular analysis of the Ccr4-Not deadenylase: relevance to human disease [PDF]
In eukaryotes, the removal of the poly (A) tail of cytoplasmic mRNA (deadenylation) is a crucial step in post-transcriptional gene regulation. A major enzyme involved in regulated mRNA deadenylation is the Ccr4-Not deadenylase, which contains two ...
Airhihen, Blessing
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Poly(A) tail regulation in stem cells and early development. [PDF]
Cell RegenMiao X, Hu G.
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Regulation of eukaryotic mRNA deadenylation and degradation by the Ccr4-Not complex. [PDF]
Front Cell Dev Biol, 2023 Pavanello L, Hall M, Winkler GS.
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CNOT10 is involved in the TTP-mediated AU-rich element-containing mRNA metabolism, independent of mRNA decay regulation. [PDF]
RNAArao Y, Williams JG, Lai WS.
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A next-generation dual guide CRISPR system for genetic interaction library screening. [PDF]
Nat CommunBurgold T +12 more
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The CCR4-NOT complex: a multifaceted sensor of molecular signals instructing eukaryotic mRNA translation and stability. [PDF]
Nucleic Acids ResCaulier G +4 more
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CNOT1 regulates circadian behaviour through Per2 mRNA decay in a deadenylation-dependent manner. [PDF]
RNA Biol, 2022 Mohamed HMA +6 more
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Insulin-Degrading Enzyme Regulates mRNA Processing and May Interact with the CCR4-NOT Complex. [PDF]
CellsBertocci B +6 more
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Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome. [PDF]
RNA, 2021 Enwerem III +9 more
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The CCR4-NOT deadenylase complex mediates tubulin autoregulation <i>via</i> specific adapters CNOT10 and CNOT11. [PDF]
MicroPubl BiolSarbanes SL, Hogg JR, Roll-Mecak A.
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