Results 61 to 70 of about 96,622 (267)
Dissolution and Permeability Properties of Co-Amorphous Formulations of Hydrochlorothiazide
Journal of Pharmaceutical Sciences, 2020 A biopharmaceutics classification system class IV drug, hydrochlorothiazide (HCT), was combined with co-formers of L-and d-arginine (ARG) and sodium lauryl sulphate (SLS) by cryomilling in 1:1 molar ratio. Co-amorphization was observed with L- and D-ARG.
Ruponen, Marika +2 more
openaire +4 more sources
Tuning interfacial domain walls in GdCo/Gd/GdCo′ spring magnets [PDF]
, 2016 Under the terms of the Creative Commons Attribution License 3.0 (CC-BY).-- et al.Spring magnets based on GdCo multilayers have been prepared to study the nucleation and evolution of interfacial domain walls (iDWs) depending on layer composition and ...
Alameda, J. M. +4 more
core +4 more sources
Molecules, 2018 The high index of simultaneous incidence of hypertension and hypercholesterolemia in the population of many countries demands the preparation of more efficient drugs.
Cecilia Martínez-Jiménez +3 more
doaj +1 more source
Study the influence of formulation process parameters on solubility and dissolution enhancement of efavirenz solid solutions prepared by hot-melt extrusion: a QbD methodology [PDF]
, 2018 The current study investigates the dissolution rate performance of amorphous solid solutions of a poorly water-soluble drug, efavirenz (EFV), in amorphous Soluplus® (SOL) and Kollidon® VA 64 (KVA64) polymeric systems.
Amin, Purnima +6 more
core +1 more source
Impact of Preparation Method in Co-Amorphous System
Sciences of Pharmacy, 2022 The co-amorphous solid dispersion system is one of the methods to improve the physicochemical characteristics and stability of a drug. With the appropriate material ratio and preparation method, a co-amorphous solid dispersion system can increase the bioavailability of the drug due to an increase in solubility. In addition, the co-amorphous system will
Amelia Soyata +3 more
openaire +1 more source
Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry, Nuclear Magnetic Resonance and X-Ray Powder Diffractometry [PDF]
, 2014 Purpose The objective of this study was to evaluate the thermal behavior of crystalline and amorphous bisoprolol fumarate and its compatibility with amorphous valsartan.
Juan A. Aguilar +3 more
core +3 more sources
Determination of Stable Co-Amorphous Drug-Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures [PDF]
, 2019 Co-amorphous drug–drug systems have been developed with the overall aim of improving the physical stability of two or more amorphous drugs. Co-amorphous systems often show good physical stability, and higher solubility and dissolution rates ...
Khorami, Keyoomars +2 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Engineering, 2020 Amorphous Sm–Co films with uniaxial in-plane anisotropy have great potential for application in information-storage media and spintronic materials. The most effective method to produce uniaxial in-plane anisotropy is to apply an in-plane magnetic field ...
Wenhui Liang +8 more
doaj +1 more source
Metals, 2022 In the paper, Tb65Ni35−xCox (x = 0, 10, 20, 30) amorphous ribbons were successfully prepared, and the glass-forming ability (GFA) of these ribbons was investigated.
Weihuo Li +5 more
doaj +1 more source