Results 71 to 80 of about 96,622 (267)

Spin dependent scattering of a domain-wall of controlled size

, 1999
Magnetoresistance measurements in the CPP geometry have been performed on single electrodeposited Co nanowires exchange biased on one side by a sputtered amorphous GdCo layer. This geometry allows the stabilization of a single domain wall in the Co wire,
A. Brataas, A. Brataas, A. Comment, B. Dieny, B. Doudin, B. Voegeli, D.L. Cox, E. Köster, G. Binasch, G. Tatara, H. Okuno, H. Okuno, H. Okuno, I. Chlebny, J. Colino, J.-E. Wegrowe, J.-E. Wegrowe, J.-E. Wegrowe, J.-E. Wegrowe, J.-P. Nozières, J.-Ph. Ansermet, J.-Ph. Ansermet, J.B.A.N. van Hoof, J.F. Gregg, J.S. Moodera, K. Mibu, Kimin Hong, L. Piraux, M. Johnson, M. Johnson, M. Viret, M.A.M. Gijs, M.N. Baibich, N. M. Dempsey, P. Gaunt, P. Levy, P.C. van Son, R. Ferré, R.P. van Gorkom, R.W. Cochrane, S. Wüchner, S.G. Kim, T. Taniyama, T. Valet, T.R. McGuire, Th.G.S.M. Rijks, U. Ebels, U. Rüdiger, U. Rüdiger, U. Rüdiger, V. Scarani, Y. Jaccard   +51 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Micro-photogrammetry as a tool for characterisation of dissolution behaviour of pharmaceutical dosage forms

British Journal of Pharmacy, 2018
The aim of this project is to develop an innovative analytical technique for the 3D chemical mapping of pharmaceutical dosage forms, via simultaneous topographic characterisation and dissolution analysis of solid drug delivery systems.
Alessandra D'Angelo, Mike Reading, Milan D Antonjievic   +2 more
doaj   +1 more source

Co-Amorphous System: A promising Strategy for Delivering Poorly Water - Soluble Drugs

Iraqi Journal of Pharmaceutical Sciences, 2020
Amorphization of drug has been considered as an attractive approach in improving drug solubility and bioavailability. Unlike their crystalline counterparts, amorphous materials lack the long-range order of molecular packing and present the highest energy
Eman S. Aldahhan, Ameera A. Radhi
doaj   +1 more source

Recent advances in dual-drug co-amorphous systems

Drug Discovery Today
Poor solubility of drugs and therapeutic candidates poses a significant challenge in drug research and development. Biopharmaceutical class II drugs exhibit limited absorption because of their weak solubility and high permeability. Co-amorphous systems (CAMs) have been studied widely as a way to improve the solubility of drugs.
Rutuja Shelke, Varalakshmi Velagacherla, Usha Yogendra Nayak   +2 more
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan

Molecules, 2021
Converting crystalline compounds into co-amorphous systems is an effective way to improve the solubility of poorly water-soluble drugs. It is, however, of critical importance for the physical stability of co-amorphous systems to find the optimal mixing ...
Rong Di, Jingwen Liu, Holger Grohganz, Thomas Rades   +3 more
doaj   +1 more source

Structural and magnetic properties of amorphous Co-W alloyed nanoparticles [PDF]

, 2011
18 páginas, 20 figuras, 4 tablas.-- PACS number(s): 75.75.Fk, 75.50.Kj, 75.30.Gw, 61.46.Df.-- et al.et al.W-capped Co nanoparticles dispersed in an alumina matrix are studied by means of high-resolution transmission electron microscopy, extended x-ray ...
Figueroa, A. I., Bartolomé, Juan, García, L. M., Bartolomé, Fernando, Magen, Cesar   +4 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Influence of hydrogen on the superconducting and the paramagnetic properties of some Zr-3d metallic glasses [PDF]

, 1995
We present the experimental results on the effects of hydrogen doping on the superconducting and paramagnetic properties of zirconium-rich (x > 0.66) Zr_x3d_1-x metallic glasses.
Kokanović, Ivan, Leontić, Boran, Lukatela, Jagoda   +2 more
core   +6 more sources