Randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD [PDF]
Yasushi Fukushima,1 Yuji Nakatani,2 Yumiko Ide,3 Hisakuni Sekino,4 Earl St Rose,5 Shahid Siddiqui,6 Andrea Maes,5 Colin Reisner5,6 1Department of Internal Medicine, Fukuwa Clinic, Tokyo, Japan; 2Department of Internal Medicine, Nakatani Hospital, Hyogo,
Fukushima Y +7 more
doaj +6 more sources
Budesonide/formoterol MDI with co-suspension delivery technology in COPD: the TELOS study. [PDF]
TELOS compared budesonide (BD)/formoterol fumarate dihydrate (FF) metered dose inhaler (BFF MDI), formulated using innovative co-suspension delivery technology that enables consistent aerosol performance, with its monocomponents and budesonide/formoterol fumarate dihydrate dry powder inhaler (DPI) in patients with moderate to very severe chronic ...
Ferguson GT +7 more
europepmc +5 more sources
Editors' perspectives: road vehicle suspension design, dynamics, and control [PDF]
This paper provides an overview of the latest advances in road vehicle suspension design, dynamics, and control, together with the authors' perspectives, in the context of vehicle ride, handling, and stability.
Cao, Dongpu +2 more
core +5 more sources
Modelling generalisation and power dissipation of flexible-wheel suspension concept for planetary surface vehicles [PDF]
Flexible-wheel (FW) suspension concept has been regarded to be one of the novel technologies for future planetary surface vehicles (PSVs). This study develops generalised models for fundamental stiffness and damping properties and power consumption ...
Cao, Dongpu +2 more
core +5 more sources
Pharmacokinetics of Co-Suspension Delivery Technology Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate (BGF MDI) and Budesonide/Formoterol Fumarate Dihydrate (BFF MDI) Fixed-Dose Combinations Compared With an Active Control: A Phase 1, Randomized, Single-Dose, Crossover Study in Healthy Adults. [PDF]
Maes A +4 more
europepmc +2 more sources
Efficacy and Safety of Glycopyrrolate/Formoterol Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Patients With COPD [PDF]
Long-acting muscarinic antagonist (LAMA)/long-acting β2-agonist (LABA) combinations are a treatment option for patients with COPD who continue to have symptoms despite treatment with a LAMA or a LABA alone. The Efficacy and Safety of PT003, PT005, and PT001 in Subjects with Moderate-to-Very Severe COPD (PINNACLE-1) (NCT01854645) and the Multi-Center ...
Martinez, Fernando J. +18 more
openaire +4 more sources
Co-suspension drug-loading technology, namely Aerosphere™, can improve fine particle fraction (FPF) and delivered dose content uniformity (DDCU). However, because of its poor drug-loading efficacy, the phospholipid carrier dosage in Aerosphere™ is ...
Quan Xi +3 more
doaj +1 more source
Dose-Ranging and Cumulative Dose Studies of Albuterol Sulfate MDI in Co-Suspension Delivery™ Technology (AS MDI; PT007) in Patients with Asthma: the ASPEN and ANTORA Trials [PDF]
Co-suspension Delivery™ Technology has been developed for the administration of albuterol sulfate pressurised inhalation suspension via metered-dose inhaler (AS MDI, PT007). We assessed the efficacy and safety of AS MDI versus Proventil® in order to determine the optimal dose of AS MDI to take to Phase III clinical trials.ASPEN (NCT03371459) and ANTORA
Christy Cappelletti +6 more
openaire +2 more sources
An Investigation on Energy Recovery Analysis of Active Suspension System [PDF]
Currently active suspension system is more applicable than passive for improving the suspension performance, ensuring the stability and passenger safety in modern automotive suspension system.
Gu, Fengshou +7 more
core +3 more sources
Correction to: Drug Delivery from an Innovative LAMA/LABA Co-suspension Delivery Technology Fixed-Dose Combination MDI: Evidence of Consistency, Robustness, and Reliability [PDF]
This article was originally published Online First without open access. After publication it was discovered that the author had ordered open access during the production process. The incorrect license was assigned to this paper due to a technical error.
Amber, Doty +7 more
openaire +2 more sources

