Current Insights in the Mechanisms of Cobra Venom Cytotoxins and Their Complexes in Inducing Toxicity: Implications in Antivenom Therapy [PDF]
Toxins, 2022 Cytotoxins (CTXs), an essential class of the non-enzymatic three-finger toxin family, are ubiquitously present in cobra venoms. These low-molecular-mass toxins, contributing to about 40 to 60% of the cobra venom proteome, play a significant role in cobra
Bhargab Kalita +2 more
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miRNAs derived from cobra venom exosomes contribute to the cobra envenomation [PDF]
Journal of Nanobiotechnology, 2023 Currently, there is an increasing amount of evidence indicating that exosomes and the miRNAs they contain are crucial players in various biological processes. However, the role of exosomes and miRNAs in snake venom during the envenomation process remains
Tianci Liao +13 more
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3D flow in the venom channel of a spitting cobra: do the ridges in the fangs act as fluid guide vanes? [PDF]
PLoS ONE, 2013 The spitting cobra Naja pallida can eject its venom towards an offender from a distance of up to two meters. The aim of this study was to understand the mechanisms responsible for the relatively large distance covered by the venom jet although the venom ...
Michael Triep +6 more
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Malaysian and Chinese King Cobra Venom Cytotoxicity in Melanoma and Neonatal Foreskin Fibroblasts Is Mediated by Age and Geography [PDF]
Toxins, 2023 Snake venoms constitute a complex, rapidly evolving trait, whose composition varies between and within populations depending on geographical location, age and preys (diets).
Bianca Op den Brouw +4 more
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Evaluation of the Lethal Potency of Scorpion and Snake Venoms and Comparison between Intraperitoneal and Intravenous Injection Routes [PDF]
Toxins, 2014 Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such stings and bites of venomous animals occur every year worldwide.
Naoual Oukkache +6 more
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Recombinant antibodies against Iranian cobra venom as a new emerging therapy by phage display technology [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: The production of antivenom from immunized animals is an established treatment for snakebites; however, antibody phage display technology may have the capacity to delivery results more quickly and with a better match to local need.
Ali Nazari +3 more
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Evaluation of Nanodiamond-in-Oil Emulsion with Snake Venom to Enhance Potent Antibody Induction in Mice and Rabbits [PDF]
NanomaterialsNanodiamonds (NDs) are an innovative material in biomedical applications based on their excellent biocompatibility, nanoscale dimensions, and high surface area.
Min-Han Lin +5 more
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Atrase A, a P-III class metalloproteinase purified from cobra venom, exhibits potent anticoagulant activity by inhibiting coagulation pathway and activating the fibrinolytic system [PDF]
HeliyonSnake venoms, comprising a complex array of protein-rich components, an important part of which are snake venom metalloproteinases (SVMPs). These SVMPs, which are predominantly isolated from viperid venoms, are integral to the pathology of snakebites ...
Xin-Jie Zhong +4 more
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Ophthalmia Secondary to Cobra Venom Spitting in the Volta Region, Ghana: A Case Report [PDF]
Case Reports in Ophthalmology, 2017 Purpose: To report the first case of ophthalmia due to contact with cobra venom in the Volta Region, Ghana. Methods: An ointment containing vitamin A was applied to treat the patient’s unilateral defects in the corneal epithelium and the consequent ...
Maria Andrea Lanzetta +4 more
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Curcumin alleviates pain and improves cognitive impairment in a rat model of cobra venom-induced trigeminal neuralgia [PDF]
Journal of Pain Research, 2018 Li Zhang,1 Xinli Ding,2 Zhe Wu,3 Min Wang,1 Ming Tian1 1Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, 2Department of Rehabilitation Medicine, Shandong Provincial Hospital Affiliated to Shandong ...
Zhang L, Ding X, Wu Z, Wang M, Tian M
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