Results 31 to 40 of about 13,049 (217)

cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage [PDF]

open access: yes, 2015
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Bate, C, Williams, A
core   +2 more sources

Biochemical and toxinological characterization of Naja sumatrana (Equatorial spitting cobra) venom

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2011
The lethal and enzymatic activities of venom from Naja sumatrana (Equatorial spitting cobra) were determined and compared to venoms from three other Southeast Asian cobras (Naja sputatrix, Naja siamensis and Naja kaouthia).
MKK Yap, NH Tan, SY Fung
doaj   +1 more source

Local Cytotoxic Effects in Cobra Envenoming: A Pilot Study

open access: yesToxins, 2022
The cobra (genus Naja (N.)) is one of the most common venomous snakes. Due to its frequency and deadly complications of muscle paralysis, local necrosis, and chronic musculoskeletal disability, it should not be ignored.
Jing-Hua Lin   +3 more
doaj   +1 more source

Leukocyte sequestration in pulmonary microvessels and lung injury following systemic complement activation in rabbits [PDF]

open access: yes, 1999
Inflammatory reactions are associated with sequestration of leukocytes in the lung. Complement activation leads to accumulation of leukocytes in alveolar septa and alveoli, to lung edema and hemorrhage.
Goetz, Alwin Eduard   +5 more
core   +1 more source

Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles

open access: yesToxins, 2020
Latest advancement of omics technologies allows in-depth characterization of venom compositions. In the present work we present a proteomic study of two snake venoms of the genus Naja i.e., Naja naja (black cobra) and Naja oxiana (brown cobra) of ...
Aisha Manuwar   +8 more
doaj   +1 more source

Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. [PDF]

open access: yes, 2017
Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies ...
Verkman, Alan S, Yao, Xiaoming
core   +2 more sources

Biochemical and morphological analysis of cell death induced by Egyptian cobra (Naja haje) venom on cultured cells

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2004
We investigated the in vitro process of cell death caused by Egyptian cobra venom on primary human embryonic kidney (293T) and mouse myoblast (C2C12) cell lines. The aim of these studies was to provide further information about triggering cell death, and
M. A. A. Omran, S. A. Fabb, G. Dickson
doaj   +1 more source

Proteomic characterization of Naja mandalayensis venom

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2021
Background Naja mandalayensis is a spitting cobra from Myanmar. To the best of our knowledge, no studies on this venom composition have been conducted so far.
Emídio Beraldo Neto   +3 more
doaj   +1 more source

Anti-Cancer Effect of Moroccan Cobra Naja haje Venom and Its Fractions against Hepatocellular Carcinoma in 3D Cell Culture

open access: yesToxins, 2021
Hepatocellular carcinoma (HCC) is the most common primary liver cancer in adults, the fifth most common malignancy worldwide and the third leading cause of cancer related death.
Ayoub Lafnoune   +15 more
doaj   +1 more source

Purification and characterization of a myotoxic phospholipase-a2 from indian cobra (Naja-Naja-Naja) venom [PDF]

open access: yes, 1989
Purification and characterization of a myotoxic phospholipase A2 from Indian cobra (Naja naja naja) venom. Toxicon27, 861–873, 1989.—A major phospholipase A2 (NN-XIII-PLA2) which constitutes 20% of the whole Naja naja naja venom was purified to ...
Bhat, M. K, Gowda, T. V
core   +1 more source

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