Study the Histopathological Effect Associated with Oral Overdose of Opioid Derivatives - on Liver and Kidney Tissue in Male Rats [PDF]
Basrah Journal of Veterinary Research, 2023 The current study aimed to ascertain the impact of acute codeine dose (0.50 and 1 ml/ 250g), on the histolopathological profile of the liver and kidney in male rats.
Yasmeen Mohammed
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Global Pediatric Health, 2021 Objective. Our objective was to examine the impact of the U.S. FDA’s 2013 black box warning against codeine on codeine and other opioid prescription filling after pediatric tonsillectomy and/or adenoidectomy (T/A) overall and by child race and provider ...
Amy Lawrence +5 more
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Cough: neurophysiology, methods of research, pharmacological therapy and phonoaudiology
International Archives of Otorhinolaryngology, 2012 Introduction: The cough is the more common respiratory symptom in children and adults. Objective: To present a revision on the neurophysiology and the methods for study of the consequence of the cough, as well as the pharmacotherapy and phonoaudiology ...
Balbani, Aracy Pereira Silveira
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Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]
, 2015 Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh +6 more
core +1 more source
The importance of 6-MAM levels and morphine/codeine ratio in diagnosis of death among drug addicts [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2019 Introduction/Objective. Heroin is metabolized to 6-monoacetylmorphine (6-MAM) and morphine. The objective of this study is to examine 6-MAM, morphine, and codeine relationships in order to distinguish deaths related to heroin consumption from deaths ...
Jakšić Vladimir +5 more
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How resistant to tampering are codeine containing analgesics on the market? Assessing the potential for opioid extraction [PDF]
, 2016 INTRODUCTION: Misuse of opioid analgesics, in combination with diversion, dependence, and fatal overdoses, presents a serious problem for public health, which affects many countries worldwide.
Breindahl, Torben +3 more
core +3 more sources
A clinical tool for reducing central nervous system depression among neonates exposed to codeine through breast milk. [PDF]
PLoS ONE, 2013 Neonates are commonly exposed to maternal codeine through breast milk. Central Nervous System (CNS) depression has been reported in up to 24% of nurslings following codeine exposure.
Lauren E Kelly +11 more
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Buprenorphine-Naloxone in the Treatment of Codeine Dependence: a Scoping Review of Clinical Case Presentations [PDF]
, 2017 Misuse of prescribed and over the counter (OTC) codeine containing medicines is an increasing public health concern in recent times. Studies have called for low threshold treatment services for individuals experiencing codeine dependence using ...
A Casati +56 more
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Medicina, 2019 Background and Objectives: Codeine requires biotransformation by the CYP2D6 enzyme, encoded by the polymorphic CYP2D6 gene, to morphine for therapeutic efficacy. CYP2D6 phenotypes of poor, intermediate, and ultra-rapid metabolisers are at risk of codeine
Helen Radford +3 more
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Codeine-induced sperm DNA damage is mediated predominantly by oxidative stress rather than apoptosis
Redox Report, 2020 Background: Opioids have been implicated to induce infertility. Although codeine remains the most used opioid for recreational purpose, no study has documented its effect on sperm quality.
Ayodeji Folorunso Ajayi +1 more
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