Results 11 to 20 of about 372,161 (260)
Molecular Biology Reports, 2021 Codon usage bias is the preferential or non-random use of synonymous codons, a ubiquitous phenomenon observed in bacteria, plants and animals. Different species have consistent and characteristic codon biases. Codon bias varies not only with species, family or group within kingdom, but also between the genes within an organism.
Sujatha Thankeswaran Parvathy +2 more
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Geographical distribution of Brucella melitensis inferred from rpoB gene variation
Journal of Infection in Developing Countries, 2017 Introduction: Currently available tests have limitations for the identification of Brucella species and strains, and their genetic lineage. The genome sequence of the rpoB gene encoding the β-subunit of DNA-dependent RNA polymerase was investigated for ...
Kim-Kee Tan +7 more
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Candidate essential genes in Burkholderia cenocepacia J2315 identified by genome-wide TraDIS
Frontiers in Microbiology, 2016 Burkholderia cenocepacia infection often leads to fatal cepacia syndrome in cystic fibrosis patients. However, antibiotic therapy rarely results in complete eradication of the pathogen due to its intrinsic resistance to many clinically available ...
Yee-Chin Wong +6 more
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Intracellular management of information: from DNA to proteins
tripleC: Communication, Capitalism & Critique, 2009 The living features of cells constitute an information flow from a central database, the nuclear DNA, to molecular effectors, proteins, which are synthesised in the cytoplasm.
Juan M. Lara
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Analysis of p53 codon 72 polymorphism and HPV 5,8 E6 oncoprotein expression in Basal cell carcinoma in Basrah [PDF]
The Medical Journal of Basrah University, 2016 Background: Two polymorphic forms of the p53 gene that codes either for Arginine or proline at codon 72 were identified, However, this individual might have one of the three genotypes: Arginine/Arginine, Proline/Proline or Arginine /Proline.
Wasan AA. Sayhood +2 more
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eLife, 2022 Engineering transfer RNAs to read codons consisting of four bases requires changes in tRNA that go beyond the anticodon sequence.
Tarana Siddika +2 more
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Characterization of the mIF4G Domains in the RNA Surveillance Protein Upf2p
Current Issues in Molecular Biology, 2023 Thirty percent of all mutations causing human disease generate mRNAs with premature termination codons (PTCs). Recognition and degradation of these PTC-containing mRNAs is carried out by the mechanism known as nonsense-mediated mRNA decay (NMD).
Edgardo M. Colón +5 more
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Effects of Arbovirus Multi-Host Life Cycles on Dinucleotide and Codon Usage Patterns
Viruses, 2019 Arthropod-borne viruses (arboviruses) of vertebrates including dengue, zika, chikungunya, Rift Valley fever, and blue tongue viruses cause extensive morbidity and mortality in humans, agricultural animals, and wildlife across the globe.
Nicole R. Sexton, Gregory D. Ebel
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Clinical and Translational Medicine, 2023 Background Translation dysregulation plays a crucial role in tumourigenesis and cancer progression. Oncogenic translation relies on the stability and availability of tRNAs for protein synthesis, making them potential targets for cancer therapy.
Peng Li +4 more
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A Novel Mutation of PARK-2 Gene in a Patient with Early-onset Parkinson’s Disease
Oman Medical Journal, 2020 Between 3–5% of all patients with Parkinson’s disease (PD) have onset before the age of 40 years, which is likely related to genetic causes. Parkin gene mutations are the most common mutations, which are associated with autosomal recessive early-onset PD.
Tariq Alafifi +4 more
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