Results 21 to 30 of about 372,161 (260)

Modulation of Escherichia coli Translation by the Specific Inactivation of tRNAGly Under Oxidative Stress

open access: yesFrontiers in Genetics, 2020
Bacterial oxidative stress responses are generally controlled by transcription factors that modulate the synthesis of RNAs with the aid of some sRNAs that control the stability, and in some cases the translation, of specific mRNAs.
Lorenzo Eugenio Leiva   +15 more
doaj   +1 more source

Evolution: are the monkeys’ typewriters rigged? [PDF]

open access: yesRoyal Society Open Science, 2014
Evolution is presumed to proceed by random mutations, which increase an individual’s fitness. Increased fitness produces a higher survival rate for those individuals within populations and drives the variants to fixation over large timescales to produce ...
Michael R. Garvin, Anthony J. Gharrett
doaj   +1 more source

Exploring Differentially Expressed Genes and Immune Modulation in Diffuse Large B-Cell Lymphoma through RNA Sequencing Analysis [PDF]

open access: yesIranian Journal of Medical Sciences
Background: Diffuse large B-cell lymphoma (DLBCL) is globally recognized as the most prevalent and aggressive subtype of non-Hodgkin lymphoma. While conventional treatments are effective initially, the disease can become resistant or relapse over time ...
Nor Adzimah Johdi   +4 more
doaj   +1 more source

A modular and optimized single marker system for generating Trypanosoma brucei cell lines expressing T7 RNA polymerase and the tetracycline repressor [PDF]

open access: yesOpen Biology, 2012
Here, we present a simple modular extendable vector system for introducing the T7 RNA polymerase and tetracycline repressor genes into Trypanosoma brucei.
S. K. Poon   +4 more
doaj   +1 more source

Developing and evaluating a pollination systems knowledge assessment in a multidisciplinary course

open access: yesInternational Journal of STEM Education, 2022
Background Although pollinators play an integral role in human well-being, their continued global decline reflects the need to provide and evaluate general pollinator knowledge to promote their conservation.
P. Citlally Jimenez   +3 more
doaj   +1 more source

Solid Phase Assembly of Fully Protected Trinucleotide Building Blocks for Codon-Based Gene Synthesis

open access: yesApplied Sciences, 2019
The use of pre-formed trinucleotides, representing codons of the 20 canonical amino acids, for oligonucleotide-directed mutagenesis offers the advantage of controlled randomization and generation of “smart libraries”. We here present a method
Ruth Suchsland   +3 more
doaj   +1 more source

Spatial and temporal variation of the phytoplankton structure in cascading oligotrophic reservoirs of southeast Brazil

open access: yesActa Limnologica Brasiliensia, 2020
: Aim Structural changes in phytoplankton was evaluated in one ultraoligotrophic and two oligotrophic cascading reservoirs during two climatic periods (austral winter and summer) of 2014. Changes in phytoplankton biomass, species composition, and codons
Ana Margarita Loaiza-Restano   +3 more
doaj   +1 more source

Strategies and Patterns of Codon Bias in Molluscum Contagiosum Virus

open access: yesPathogens, 2021
Trends associated with codon usage in molluscum contagiosum virus (MCV) and factors governing the evolution of codon usage have not been investigated so far.
Rahul Raveendran Nair   +4 more
doaj   +1 more source

The Dynamic Codon Biaser: calculating prokaryotic codon usage biases

open access: yesMicrobial Genomics, 2021
Bacterial genomes often reflect a bias in the usage of codons. These biases are often most notable within highly expressed genes. While deviations in codon usage can be attributed to selection or mutational biases, they can also be functional, for example controlling gene expression or guiding protein structure.
Brian Dehlinger   +3 more
openaire   +3 more sources

Identification and characterization of Daldinia eschscholtzii isolated from skin scrapings, nails, and blood [PDF]

open access: yesPeerJ, 2016
Background Daldinia eschscholtzii is a filamentous wood-inhabiting endophyte commonly found in woody plants. Here, we report the identification and characterization of nine D. eschscholtzii isolates from skin scrapings, nail clippings, and blood. Methods
Kee Peng Ng   +9 more
doaj   +2 more sources

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