Results 41 to 50 of about 616,369 (340)

The Mystery of Two Straight Lines in Bacterial Genome Statistics. Release 2007

open access: yes, 2007
In special coordinates (codon position--specific nucleotide frequencies) bacterial genomes form two straight lines in 9-dimensional space: one line for eubacterial genomes, another for archaeal genomes. All the 348 distinct bacterial genomes available in
A. Carbone   +25 more
core   +4 more sources

Solving the riddle of codon usage preferences: a test for translational selection [PDF]

open access: yes, 1998
Translational selection is responsible for the unequal usage of synonymous codons in protein coding genes in a wide variety of organisms. It is one of the most subtle and pervasive forces of molecular evolution, yet, establishing the underlying causes ...
A Kaminskii   +17 more
core   +3 more sources

Spatial and temporal variation of the phytoplankton structure in cascading oligotrophic reservoirs of southeast Brazil

open access: yesActa Limnologica Brasiliensia, 2020
: Aim Structural changes in phytoplankton was evaluated in one ultraoligotrophic and two oligotrophic cascading reservoirs during two climatic periods (austral winter and summer) of 2014. Changes in phytoplankton biomass, species composition, and codons
Ana Margarita Loaiza-Restano   +3 more
doaj   +1 more source

Strategies and Patterns of Codon Bias in Molluscum Contagiosum Virus

open access: yesPathogens, 2021
Trends associated with codon usage in molluscum contagiosum virus (MCV) and factors governing the evolution of codon usage have not been investigated so far.
Rahul Raveendran Nair   +4 more
doaj   +1 more source

The Dynamic Codon Biaser: calculating prokaryotic codon usage biases

open access: yesMicrobial Genomics, 2021
Bacterial genomes often reflect a bias in the usage of codons. These biases are often most notable within highly expressed genes. While deviations in codon usage can be attributed to selection or mutational biases, they can also be functional, for example controlling gene expression or guiding protein structure.
Brian Dehlinger   +3 more
openaire   +3 more sources

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapyinduced leukemia [PDF]

open access: yes, 2001
Glutathione S-transferases (GSTs) detoxify potentially mutagenic and toxic DNA-reactive electrophiles, including metabolites of several chemotherapeutic agents, some of which are suspected human carcinogens.
Allan, J.M.   +9 more
core   +4 more sources

Identification and characterization of Daldinia eschscholtzii isolated from skin scrapings, nails, and blood [PDF]

open access: yesPeerJ, 2016
Background Daldinia eschscholtzii is a filamentous wood-inhabiting endophyte commonly found in woody plants. Here, we report the identification and characterization of nine D. eschscholtzii isolates from skin scrapings, nail clippings, and blood. Methods
Kee Peng Ng   +9 more
doaj   +2 more sources

Codon usage and codon context bias in Xanthophyllomyces dendrorhous [PDF]

open access: yesBMC Genomics, 2015
Synonymous codons are used differentially in organisms from the three domains of life, a phenomenon referred to as codon usage bias. In addition, codon pair bias, particularly in the 3' codon context, has also been described in several organisms and is associated with the accuracy and rate of translation. An improved understanding of both types of bias
Baeza Cancino, Marcelo   +4 more
openaire   +5 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Antigenic and immunogenic properties of the canine distemper virus nucleocapsid protein expressed in Escherichia coli employing codon optimized synthetic gene

open access: yesPesquisa Veterinária Brasileira
: Despite common occurrence and importance of canine distemper disease the majority of tests currently available for diagnosis are hampered by either low sensitivity or specificity. In this study it was evaluated antigenic and immunogenic characteristics
Maureen H.V. Fernandes   +6 more
doaj   +1 more source

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