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Codon usage bias is the preferential or non-random use of synonymous codons, a ubiquitous phenomenon observed in bacteria, plants and animals. Different species have consistent and characteristic codon biases. Codon bias varies not only with species, family or group within kingdom, but also between the genes within an organism.
Sujatha Thankeswaran Parvathy +2 more
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A general model of codon bias due to GC mutational bias.
BackgroundIn spite of extensive research on the effect of mutation and selection on codon usage, a general model of codon usage bias due to mutational bias has been lacking.
Gareth A Palidwor +2 more
doaj +4 more sources
On ribosome load, codon bias and protein abundance. [PDF]
Different codons encoding the same amino acid are not used equally in protein-coding sequences. In bacteria, there is a bias towards codons with high translation rates.
Stefan Klumpp, Jiajia Dong, Terence Hwa
doaj +2 more sources
Synonymous codon usage defines functional gene families [PDF]
Background The degeneracy of the genetic code is increasingly recognized for roles in regulating translation rate, protein folding, and cell response. However, the functional genomics of codon usage patterns remains poorly defined.
Farzan Ghanegolmohammadi +5 more
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Eukaryotic evolutionary transitions are associated with extreme codon bias in functionally-related proteins. [PDF]
Codon bias in the genome of an organism influences its phenome by changing the speed and efficiency of mRNA translation and hence protein abundance. We hypothesized that differences in codon bias, either between-species differences in orthologous genes ...
Nicholas J Hudson +5 more
doaj +1 more source
Causes and implications of codon usage bias in RNA viruses. [PDF]
Choice of synonymous codons depends on nucleotide/dinucleotide composition of the genome (termed mutational pressure) and relative abundance of tRNAs in a cell (translational pressure).
Ilya S Belalov, Alexander N Lukashev
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Analysis of codon usage pattern in Lonicera × heckrottii ‘Gold Flame’ based on chloroplast genome
Codon usage bias (CUB) was a unique feature of the genome, and revealing chloroplast genome codon usage bias can provide useful information for the evolution of plant species.
Jiaqiang ZHANG +3 more
doaj +1 more source
Comparative analysis of codon usage bias and codon context patterns between dipteran and hymenopteran sequenced genomes. [PDF]
Codon bias is a phenomenon of non-uniform usage of codons whereas codon context generally refers to sequential pair of codons in a gene. Although genome sequencing of multiple species of dipteran and hymenopteran insects have been completed only a few of
Susanta K Behura, David W Severson
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Comparative analysis of codon usage patterns of FUT2 from different species
Enterotoxigenic E. coli is an important zoonotic pathogen causing diarrhea in human and newborn animals. α - (1,2) fucosyltransferase 2 (FUT2) is closely associated with the formation of pathogenic receptors of Enterotoxigenic E. coli.
Chao Xu +3 more
doaj +1 more source
Codon usage bias in radioresistant bacteria [PDF]
AbstractThe relationship between patterns of codon usage bias (CUB), the preferential usage of synonimous nucleotide triplets encoding the same amino acid, and radioresistance was investigated int he genomes of 16 taxonomically distinct radioresistant prokaryotic organisms and in a control set of 11 non-radioresistant bacteria.
Dilucca M. +3 more
openaire +4 more sources

