Results 91 to 100 of about 1,577,940 (309)

Liver Antioxidants in Relation to Beak Morphology, Gizzard Size and Diet in the Common Eider Somateria mollissima

open access: yesAntioxidants, 2019
Antioxidants in the liver are particularly abundant in capital breeders that rely on stored resources for egg production. Capital breeders like eider (hereafter common eider) Somateria mollissima have disproportionately large livers with low levels of ...
Anders Pape Møller   +2 more
doaj   +1 more source

Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER–mitochondria contacts

open access: yesJournal of Cell Biology, 2019
Coenzyme Q (CoQ) lipids are ancient electron carriers that, in eukaryotes, function in the mitochondrial respiratory chain. In mitochondria, CoQ lipids are built by an inner membrane–associated, multicomponent, biosynthetic pathway via successive steps ...
Kelly Subramanian   +9 more
semanticscholar   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge   +9 more
wiley   +1 more source

The Important Role of CoQ10 in Aging

open access: yesAntioxidants, 2019
Coenzyme Q10 (CoQ10) is an essential lipid present in all cell membranes[...]
Guillermo López-Lluch
doaj   +1 more source

Preparation of Neurospora crassa mitochondria [PDF]

open access: yes, 1978
The fungus Neurospora crassa represents a eukaryotic cell with high biosynthetic activities. Cell mass doubles in 2-4 hr during expone ntial growth , even in simple salt media with sucrose as the sole carbon source. The microorgani sm forms a mycelium of
Jacki   +11 more
core   +2 more sources

Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6

open access: yesOxidative Medicine and Cellular Longevity, 2019
Coenzyme Q (CoQ), a redox-active lipid, is comprised of a quinone group and a polyisoprenoid tail. It is an electron carrier in the mitochondrial respiratory chain, a cofactor of other mitochondrial dehydrogenases, and an essential antioxidant.
Manuel J Acosta Lopez   +17 more
semanticscholar   +1 more source

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

open access: yesAdvanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang   +7 more
wiley   +1 more source

Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry

open access: yesAngewandte Chemie, EarlyView.
Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang   +7 more
wiley   +2 more sources

PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance PARL is a peculiar protease in the inner membrane of mitochondria with important but unclear physiological roles and with links to Parkinson’s disease and diabetes.
M. Spinazzi   +12 more
semanticscholar   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

open access: yesAdvanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy