Results 111 to 120 of about 42,231 (222)

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, Volume 13, Issue 43, 3 August 2026.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

Advanced Science, Volume 13, Issue 44, 7 August 2026.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang, Peipei Song, Xueji Wu, Lei Wang, Wei Xie, Pinning Feng, Chao Cheng, Jianping Guo   +7 more
wiley   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, Volume 4, Issue 3, Page 278-292, August 2026.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Coenzyme Q

Journal of Synthetic Organic Chemistry, Japan, 1969
SATO, Kikumasa, MATSUURA, Tsuneo, INOUE, Seiichi   +2 more
openaire   +2 more sources

Atorvastatin‐Associated Severe Bradyarrhythmia Following Multiorgan Dysfunction: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Statins are the primary treatment for hypercholesterolemia and a cornerstone of atherosclerotic cardiovascular disease prevention. Although generally safe, serious adverse effects may occur in selected patients, particularly when statins are used at high doses or without medical supervision.
Xiao‐Qing Kou, Yan‐Zhen Wang, Yi‐Rong Gan, Yun‐Long Zhang, Shu‐Yun He, Zheng Zhang   +5 more
wiley   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Microbial Oxidative Stress in Food Fermentations: A Comprehensive Review

eFood, Volume 7, Issue 4, August 2026.
Oxidative stress has a dual role in food fermentations: low ROS supports adaptive signaling, whereas excessive ROS causes cellular damage and process inhibition. Managing redox state as a controllable process variable can improve fermentation robustness and final food quality.
Wanrong Hu, Manxi Wu, Hui Xu, Jiebiao Chen, Wen Cai, Han Yang, Hujing Cao, Xinlin Huang, Jinping Cao, Chongde Sun, Yue Wang, Dongliang Li   +11 more
wiley   +1 more source

Mitochondria limit coenzyme Q export under cholesterol biosynthetic stress. [PDF]

J Cell Biol
Ndoci M, Bhattacharya S, Agrawal I, Hinze Y, Lemke K, Schumacher AL, Uijttewaal E, Elling U, Lawo S, Giavalisco P, Langer T, Deshwal S.   +11 more
europepmc   +1 more source

Network Pharmacology Combined With Metabonomics and Transcriptomics Reveals the Mechanism of Rubus Chingii Hu in Alleviating Nephrotoxicity Caused by Tripterygium Glycosides Tablet

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Flow chart of RCH to improve TGT‐induced nephrotoxicity. ABSTRACT Researches on Tripterygium glycosides tablets (TGT) often overlook renal toxicity from prolonged use. Rubus chingii Hu (RCH) is beneficial to kidney health and has an unclear role in reducing nephrotoxicity.
Cong Zhang, Zepeng Zhang, Tong Zhou, Lei Zhang   +3 more
wiley   +1 more source

Spatial mapping of CoQ10 repletion by BPM31510 in a genetic mouse model (Coq4^F147C) of coenzyme Q deficiency. [PDF]

J Lipid Res
Barriocanal-Casado E, Stopka SA, Pesini A, Aristizabal-Henao JJ, Karmacharya S, Van Cura D, Zhang R, Nickerson KR, Grover K, Zavidij O, Wessel SR, Narain NR, Modur V, Gesta S, Kiebish MA, Quinzii CM.   +15 more
europepmc   +1 more source