Results 121 to 130 of about 1,766,693 (250)
, 2013 Parkinson's disease is characterized by dopamine cell loss of the substantia nigra. Parkinson's disease and the neurotoxin 1-methyl-4-phenyl-1,2,5,6 tetrahydropyridine may destroy dopamine neurons through oxidative stress.
Roth, Robert H. +12 more
core +1 more source
Allergy, EarlyView.Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang +12 more
wiley +1 more source
Metal binding and antioxidative properties of novel Coenzyme Q-0 derivatives [PDF]
, 2013 Many organic compounds having a benzoquinone structure show diversity of physiologically important properties and they are explored as antitumor, antibacterial, and antioxidative systems.
Koleva Gudeva, Liljana +3 more
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer +5 more
wiley +1 more source
Coenzyme Q 10 Abrogates Flutamide-induced Hepatotoxicity in Albino Rats
Journal of Medical Sciences and Health, 2019 Aim: The efficacy and therapeutic benefit of flutamide (FLU) can be clinically limited by the occurrence of hepatotoxicity which may progress to liver failure.
Elias Adikwu +2 more
doaj
Voice Fundamental Frequency Variation and Statin Therapy
Clinical Otolaryngology, EarlyView.ABSTRACT Objectives Statins are considered a first‐line treatment for dyslipidaemia, being the most frequently prescribed medicine worldwide. However, statin therapy has been associated with several adverse effects, including statin‐associated myopathy, which may manifest with symptoms such as myalgia, muscle stiffness, and cramps.
Luca Francesco Parata +5 more
wiley +1 more source
The importance of plasma membrane coenzyme Q in aging and stress responses
, 2007 7 páginas, 1 figura.The plasma membrane of eukaryotic cells is the limit to interact with the environment. This position implies receiving stress signals that affects its components such as phospholipids.
Cabo, Rafael de +2 more
core +1 more source
A 3D Bioprinted Platform That Maintains the Functional Integrity of Primary AML Cells
Cell Proliferation, EarlyView.This study presents a 3D bioprinted platform using gelatin‐hyaluronic acid hydrogels to enhance primary AML cell survival and proliferation while preserving stem‐like properties in vitro. By recapitulating in vivo‐like metabolic activity and drug resistance, this system offers a robust tool for preclinical drug screening and personalised therapy ...
Wanling Huang +10 more
wiley +1 more source
Mitochondrial respiration and characteristics of skeletal muscles in children with cerebral palsy
Developmental Medicine &Child Neurology, EarlyView.Skeletal muscles utilize numerous mitochondria for energy production needed during muscle contraction. Mitochondria produce this energy through the electron transport chain. After an injury such as ACL‐injury in typically developing children, there is a reduction in muscle mitochondrial respiration and content.
Sudarshan Dayanidhi +10 more
wiley +1 more source
The Way to Determine Coenzyme Q
Journal of the American College of Cardiology, 2013 Coenzyme Q (CoQ, ubiquinone) is a lipophilic molecule present in all cells, located mainly in the inner mitochondrial membrane. It is composed of a redox active benzoquinone ring conjugated to an isoprenoid chain.
openaire +2 more sources