Results 71 to 80 of about 1,766,693 (250)
Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis
Advanced Science, EarlyView.Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran +10 more
wiley +1 more source
Metabolism and function of coenzyme Q
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2004 Coenzyme Q (CoQ) is present in all cells and membranes and in addition to be a member of the mitochondrial respiratory chain it has also several other functions of great importance for the cellular metabolism. This review summarizes the findings available to day concerning CoQ distribution, biosynthesis, regulatory modifications and its participation ...
Turunen, Mikael +2 more
openaire +2 more sources
Studies on Coenzyme Q Contents in Serum LipoproteinsPart Ⅱ. Changes in the Concentrations of Coenzyme Q(9) and α-tocopherol in Rats with IsoproterenolInduced Myocardial Necrosis [PDF]
, 1984 Myocardial necrosis was induced experimentally by the method of Rona, and coenzyme Q(9) and α-tocopherol concentrations were measured in the serum and lipoprotein fractions.
Minami, Nobuhito
core
Advanced Science, EarlyView.This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang +10 more
wiley +1 more source
Antioxidants, 2019 Antioxidants in the liver are particularly abundant in capital breeders that rely on stored resources for egg production. Capital breeders like eider (hereafter common eider) Somateria mollissima have disproportionately large livers with low levels of ...
Anders Pape Møller +2 more
doaj +1 more source
Coenzyme Q is irreplaceable by demethoxy‐coenzyme Q in plasma membrane ofCaenorhabditis elegans [PDF]
FEBS Letters, 2006 A procedure was developed to isolate fractions enriched in plasma membrane fromCaenorhabditis elegans. Coenzyme Q9(Q9) was found in plasma membrane isolated from either wild‐type or long‐livedqm30andqm51 clk‐1mutant strains ofCaenorhabditis elegans, along with dietary coenzyme Q8(Q8) and the biosynthetic intermediate demethoxy‐Q9(DMQ9).
Arroyo, Antonio +6 more
openaire +3 more sources
An isoprene lipid binding protein promotes eukaryotic coenzyme Q biosynthesis. Lohman et al.
, 2019 These are the raw image data for An isoprene lipid binding protein promotes eukaryotic coenzyme Q ...
Sutter, J (via Mendeley Data) +2 more
core +1 more source
Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria
Advanced Science, EarlyView.A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng +8 more
wiley +1 more source
The current coenzyme Q science and knowledge
, 2020 Coenzyme Q (CoQ) is a redox lipid essential for aerobic respiration and antioxidant protection. It is synthesized in each cell by a multiprotein complex inside mitochondria and incorporated in all cellular membranes.
Plácido Navas, Navas, Plácido
core +1 more source
Advanced Science, EarlyView.HADHA K406 lactylation fuels fatty acid β‐oxidation and HMGCR‐dependent cholesterol biosynthesis, fostering immunosuppressive MDSCs and exhausted CD8+ T cells in gastric cancer. Loss of this modification blocks cholesterol production, remodels the tumor microenvironment, and tumor growth is suppressed via combined inhibition of HMGCR and LDHA ...
Maoxiao Feng +10 more
wiley +1 more source