Results 191 to 200 of about 1,577,940 (309)

Convergent Evolution and De Novo Reconstitution of Apiin Biosynthesis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Apiin, an active flavonoid apioside, occurs in phylogenetically distant plants, such as parsley and chilli pepper (Capsicum annuum L.). Its sporadic distribution suggests the existence of convergent apiin biosynthesis; however, the molecular mechanisms underlying this convergence remain unclear.
Zhen Xu, Zheng‐Shuang Zhu, Hai‐Zhu Jia, Jian‐Qiang Kong   +3 more
wiley   +1 more source

Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q. [PDF]

Open Biol, 2023
Diquigiovanni C, Rizzardi N, Kampmeier A, Liparulo I, Bianco F, De Nicolo B, Cataldi-Stagetti E, Cuna E, Severi G, Seri M, Bertrand M, Haack TB, Marina AD, Braun F, Fato R, Kuechler A, Bergamini C, Bonora E.   +17 more
europepmc   +1 more source

3‐Methyl‐1‐Butanol Enhances Postharvest Resistance of Red Grapes to Botrytis cinerea by Activating Phenylpropanoid Metabolism and Antioxidant Defences

Plant Biotechnology Journal, EarlyView.
ABSTRACT Grey mould, caused by Botrytis cinerea, is a significant postharvest disease leading to substantial economic losses in the grape industry. This study investigated the regulatory mechanism of 3‐methyl‐1‐butanol (3M1B), a yeast volatile substance, on B. cinerea resistance in red grapes (Vitis vinifera L.).
Shunjie Zhai, Huijing Guo, Tongrui Sun, Minrui Guo, Jiluan Chen, Jiankang Cao, Wanting Yang, Guogang Chen   +7 more
wiley   +1 more source

Coenzyme Q improves mitochondrial and muscle dysfunction caused by CUG expanded repeats in Caenorhabditis elegans. [PDF]

Genetics
Teixeira J, Harju AM, Othman A, Eriksson O, Battersby BJ, Garcia SMDA.   +5 more
europepmc   +1 more source

A Near Telomere‐to‐Telomere Genome of Belamcanda chinensis Provides Insights Into Genome Evolution and the Biosynthesis of Characteristic Isoflavones

Plant Biotechnology Journal, EarlyView.
ABSTRACT Belamcanda chinensis is a non‐leguminous medicinal plant rich in bioactive isoflavones; however, the lack of a high‐quality reference genome has limited elucidation of its isoflavone biosynthetic and modification network. Here, we present the first near telomere‐to‐telomere genome assembly of B.
Yuan‐Yuan Wang, Bi‐Huan Chen, Gui‐Sheng Xiang, Yi‐Na Wang, Run Yang, Xiao‐Bo Li, Shi‐Yan Yuan, Yu‐Cheng Zhao, Guang‐Hui Zhang, Min‐Jian Qin, Sheng‐Chao Yang   +10 more
wiley   +1 more source

Identification of a new <i>COQ4</i> spliceogenic variant causing severe primary coenzyme Q deficiency. [PDF]

Mol Genet Metab Rep
Alcázar-Fabra M, Østergaard E, Fernández-Ayala DJM, Desbats MA, Morbidoni V, Tomás-Gallado L, García-Corzo L, Blanquer-Roselló MDM, Bartlett AK, Sánchez-Cuesta A, Sena L, Cortés-Rodríguez A, Cascajo-Almenara MV, Pagliarini DJ, Trevisson E, Gronborg SW, Brea-Calvo G.   +16 more
europepmc   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

Physiological metabolic analysis and process optimization of hypoxia in promoting coenzyme Q₁₀ biosynthesis and accumulation in <i>Rhodobacter sphaeroides</i> HY01. [PDF]

Synth Syst Biotechnol
Li B, Ge Y, Fu L, Guo H, Mohsin A, Li J, Wu J, Chen B, Zhuang Y, Wang Z.   +9 more
europepmc   +1 more source

Skeletal muscle adaptation to muscle activity and hypoxia: Differential structural and metabolic remodelling

The Journal of Physiology, EarlyView.
Abstract figure legend There has been controversy about the structural (capillary) response of skeletal muscle to altered O2 status, involving decreased supply (hypoxia) or increased demand (activity). Here we demonstrate that seven days of activation of skeletal muscle by indirect electrical stimulation led to significant expansion of the capillary ...
David Hauton, Roger W.P. Kissane, James McCullagh, Stuart Egginton   +3 more
wiley   +1 more source

The Extract of Camellia Seed Cake Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Mice by Promoting Coenzyme Q Synthesis. [PDF]

Nutrients
Chen X, Chen B, Li Z, Ma L, Zhu Q, Liu C, He H, Zhang Z, Zhou C, Liu G, Zhou Y, Deng S, Guo S, Chen Y.   +13 more
europepmc   +1 more source