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Biochemical, histological, and immunohistochemical study on the therapeutic effects and mechanism of coenzyme Q₁₀ in type 2 diabetes mellitus. [PDF]

Res Pharm Sci
Khalil MI, Monfared AL, Mahmood HB.
europepmc   +1 more source

Enhanced PrrAB system activation and restricted farnesyl pyrophosphate diversion underlie high coenzyme Q₁₀ accumulation in <i>Rhodobacter sphaeroides</i> HY01. [PDF]

Synth Syst Biotechnol
He X, Wang H, Liang M, Wang W, Chen B, Li D, Zhang L, Tan GY.   +7 more
europepmc   +1 more source

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The diversity of coenzyme Q function

Molecular Aspects of Medicine, 1997
Coenzyme Q is uniquely designed as an electron and proton carrier within the lipid phase of membranes. It now appears that this unique chemistry has diverse application to important functions in all cellular membranes. The first function of coenzyme Q was defined in the energy transduction process in mitochondria.
Placido Navas, Frederick L Crane, F L Crane   +2 more
exaly   +3 more sources

Coenzyme Q and Phenylketonuria

Nature, 1964
INVESTIGATIONS by Olson's group1,2 of the biosynthesis of coenzyme Q9 (ubiquinone-45) in the rat have shown that phenylalanine is a metabolic precursor of the benzoquinoid ring of coenzyme Q. Presumably, hydroxylation of phenylalanine to yield tyrosine would be an intermediate step in the biosynthesis of coenzyme Q (ref. 3).
E A, NAPIER, R W, KREYDEN, K S, HENLEY, H M, POLLARD   +3 more
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Coenzyme Q as an Antiadipogenic Factor

Antioxidants & Redox Signaling, 2011
Coenzyme Q (CoQ) is not only the single antioxidant synthesized in humans but also an obligatory element of mitochondrial functions. We have previously reported CoQ deficiency in white adipose tissue of ob/ob mice.
Bour, Sandy, Carmona, Maria-Carmen, Galinier, Anne, Caspar-Bauguil, Sylvie, van Gaal, Luc, Staels, Bart, Pénicaud, Luc, Casteilla, Louis   +7 more
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The function of coenzyme Q in mitochondria

The Clinical Investigator, 1993
We have accumulated evidence that coenzyme Q (CoQ) concentration in the mitochondrial membrane is not saturating for NADH oxidation but is saturating for succinate and glycerol-3-phosphate oxidation. As a result of its kinetic properties CoQ concentration changes must yield changes in respiration rates.
LENAZ G, FATO R, CASTELLUCCIO C, GENOVA ML, BOVINA C, ESTORNELL E, VALLS V, PALLOTTI, FRANCESCO, CASTELLI GP   +8 more
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The evolution of coenzyme Q

BioFactors, 2008
AbstractIn the 50 years since the identification of coenzyme Q as an electron carrier in mitochondria, it has been identified with diverse and unexpected functions in cells. Its discovery came as a result of a search for electron carriers in mitochondria following the identification of flavin and cytochromes by Warburg, Keilin, Chance and others.
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Coenzyme Q. Li. New data on the distribution of coenzyme Q in nature

Archives of Biochemistry and Biophysics, 1964
The heart of the rhesus monkey was found to contain coenzyme Q 10 . This experimental primate may serve as a model for studies of CoQ 10 as it may relate to human disease. Frog nerve tissue was also found to contain CoQ 10 . Such tissue may be a useful system for researches on CoQ in nerve physiology.
P H, GALE, R E, ERICKSON, A C, PAGE, K, FOLKERS   +3 more
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Estimation of individual coenzyme Q homolgues in a coenzyme Q mixture by densitometry

Journal of Chromatography A, 1972
Abstract A method for the densitometric determination of coenzymes Q individual homologues after separation by reversed-phase paper chromaography is described. The parameters associated with the reproducibility and accuracy of the method are discussed.
A C, Casey, P, Myers, A, Lee
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The Multiple Functions of Coenzyme Q

Bioorganic Chemistry, 2001
The coenzyme function of ubiquinone was subject of extensive studies in mitochondria since more than 40 years. The catalytic activity of ubiquinone (UQ) in electron transfer and proton translocation in cooperation with mitochondrial dehydrogenases and cytochromes contributes essentially to the bioenergetic activity of ATP synthesis.
H, Nohl, A V, Kozlov, K, Staniek, L, Gille   +3 more
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