Results 161 to 170 of about 105,879 (276)
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. [PDF]
Diaz-Vegas A +17 more
europepmc +1 more source
Adaptation of mitochondrial bioenergetics to coenzyme Q deficiency in human endothelial cells after chronic exposure to bisphosphonates. [PDF]
Budzinska A +3 more
europepmc +1 more source
Editorial: Coenzyme Q Redox State and Cellular Homeostasis
Alberto Sanz, Placido Navas
doaj +1 more source
MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen +12 more
wiley +1 more source
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans +8 more
wiley +1 more source
Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q. [PDF]
Diquigiovanni C +17 more
europepmc +1 more source
Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian +11 more
wiley +1 more source
Mitochondrial-ER Contact Sites and Tethers Influence the Biosynthesis and Function of Coenzyme Q. [PDF]
Novales NA +4 more
europepmc +1 more source
Flow chart of the study population. ABSTRACT Objectives To investigate the associations of the healthy eating index (HEI) and subclinical myocardial injury (SCMI) in different smoking statuses (current smokers, former smokers, and never smokers) based on the National Health and Nutrition Examination Survey (NHANES) III.
Zhi‐jin Li, Bin‐gui Li
wiley +1 more source

