Results 151 to 160 of about 1,766,693 (250)

Mitochondrial Reactive Oxygen Species Production in Rat Tissues with Different Contents of Reduced Coenzyme Q

Data for an article published in Antioxidants 2021 (10) "The Relationship between Mitochondrial Reactive Oxygen Species Production and Mitochondrial Energetics in Rat Tissues with Different Contents of Reduced Coenzyme ...
Dominiak, K
core   +1 more source

Dichloroacetate Improves Animal Survival, Growth, Neuromuscular Activity, Mitochondrial Stress and Physiology, and Elevated Lactate in C. elegans pdha‐1 and dld‐1 RNAi Models of Pyruvate Dehydrogenase Complex Deficiency (PDCD)

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Pyruvate dehydrogenase complex (PDHc) deficiency (PDCD) is a primary mitochondrial disorder characterized by neurodevelopmental disability, altered intermediary metabolism, and early mortality. Dichloroacetate (DCA), a pyruvate analog, activates PDHc and remains under clinical investigation for treatment of PDCD.
Cristina Remes, Neal D. Mathew, Victoria Miranda, Suraiya Haroon, Tyler O'Hara, Vernon E. Anderson, Manuela Lavorato, Kelsey Keith, Rui Xiao, Eiko Nakamaru‐Ogiso, Marni J. Falk   +10 more
wiley   +1 more source

Gastric Cancer: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 11, November 2026.
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin, Xingya Wang, Yangtao Wu, Qian Liu, Qian Ren, Hui Wang, Jingbo Zhai   +6 more
wiley   +1 more source

Editorial: Coenzyme Q Redox State and Cellular Homeostasis

Frontiers in Physiology, 2018
Alberto Sanz, Placido Navas
doaj   +1 more source

Mitochondria limit coenzyme Q export under cholesterol biosynthetic stress. [PDF]

J Cell Biol
Ndoci M, Bhattacharya S, Agrawal I, Hinze Y, Lemke K, Schumacher AL, Uijttewaal E, Elling U, Lawo S, Giavalisco P, Langer T, Deshwal S.   +11 more
europepmc   +1 more source

Diabetic Polyneuropathy Patients Exhibit an Altered Skeletal Muscle Proteome Phenotype

PROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Purpose Diabetic polyneuropathy (DPN) is a debilitating complication of diabetes that affects motor nerves and may impair skeletal muscle health. This study investigated skeletal muscle proteomic alterations associated with DPN compared with type 2 diabetes without DPN (T2D) and healthy controls (CON).
Frederik Forsberg Thybo, Karolina Snopek Khan, Jesper Emil Jakobsgaard, Henning Andersen, Kristian Vissing, Johan Palmfeldt   +5 more
wiley   +1 more source

Metabolomic Signatures of Longevity in Bivalves Reveal Reorganization of TCA Cycle and Amino Acid Metabolism

Aging Cell, Volume 25, Issue 11, November 2026.
Targeted metabolomics of gill and mantle tissues from five marine bivalve species spanning lifespans from approximately 30 to over 500 years revealed longevity‐associated metabolic signatures. Longer‐lived species exhibited reduced free amino acid pools, lactate, pyruvate‐related ratios, fumarate and malate, alongside increased succinate‐to‐fumarate ...
Pauline Bertrand, Clément J. L. Chevret, Enrique Rodríguez, Hélène Lemieux, Pierre U. Blier   +4 more
wiley   +1 more source

Spatial mapping of CoQ10 repletion by BPM31510 in a genetic mouse model (Coq4^F147C) of coenzyme Q deficiency. [PDF]

J Lipid Res
Barriocanal-Casado E, Stopka SA, Pesini A, Aristizabal-Henao JJ, Karmacharya S, Van Cura D, Zhang R, Nickerson KR, Grover K, Zavidij O, Wessel SR, Narain NR, Modur V, Gesta S, Kiebish MA, Quinzii CM.   +15 more
europepmc   +1 more source

Association of Vitamin B6 and Homocysteine–ACTH Coupling With Depressive and Anxiety Symptoms in Burning Mouth Syndrome: An Exploratory Case–Control Study

Journal of Oral Rehabilitation, Volume 53, Issue 11, Page 2053-2063, November 2026.
In this exploratory case–control study, plasma PLP (vitamin B6), homocysteine and ACTH concentrations did not differ between patients with burning mouth syndrome (BMS) and controls, and none discriminated patients individually. Within patients, however, psychological distress mapped onto a homocysteine–ACTH relationship from which PLP appeared ...
Ashley Lebel, Charlotte Guillouet, André Porporatti, Yves Boucher   +3 more
wiley   +1 more source

Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis. [PDF]

Nat Metab
Strefeler A, Baker ZN, Chollet S, Foged MM, Guerra RM, Ivanisevic J, Gallart-Ayala H, Pagliarini DJ, Jourdain AA.   +8 more
europepmc   +1 more source