Results 191 to 200 of about 105,879 (276)
Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang +7 more
wiley +2 more sources
An AlphaFold Structure Analysis of COQ2 as Key a Component of the Coenzyme Q Synthesis Complex. [PDF]
Antioxidants (Basel)Vargas-Pérez MLÁ +2 more
europepmc +1 more source
Repurposing Hetrombopag for Multiple Myeloma by Targeting PNPO: A Celastrol‐Inspired Approach
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 5, May 2026.Hetrombopag targeted PNPO to inhibit multiple myeloma. ABSTRACT Multiple myeloma (MM) is a malignancy of plasma cells whose excessive immunoglobulin production elevates reactive oxygen species (ROS), promoting pathogenesis. Active compounds from Traditional Chinese Medicine, such as celastrol, can exert antitumour effects by further increasing ROS ...
Tianyi Yu +9 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 5, May 2026.This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang +10 more
wiley +1 more source
Rapid HPLC method reveals dynamic shifts in coenzyme Q redox state. [PDF]
J Biol ChemVitvitsky V +4 more
europepmc +1 more source
The FEBS Journal, Volume 293, Issue 9, Page 2673-2691, May 2026.Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova +5 more
wiley +1 more source
Causes of low muscle coenzyme-Q levels beyond primary coenzyme-Q-deficiency
Molecular Genetics and Metabolism Reports, 2018 Finsterer, Josef, Zarrouk-Mahjoub, Sinda
openaire +2 more sources
EFSA Journal, Volume 24, Issue 5, May 2026.Abstract The food enzyme catalase (hydrogen‐peroxide:hydrogen‐peroxide oxidoreductase; EC 1.11.1.6) is produced with the non‐genetically modified Aspergillus tubingensis strain AE‐CN by Amano Enzyme Inc. The food enzyme is intended to be used in seven food manufacturing processes.
EFSA Panel on Food Enzymes (FEZ) +17 more
wiley +1 more source