The Relationship between Coenzyme Q10, Oxidative Stress, and Antioxidant Enzymes Activities and Coronary Artery Disease [PDF]
A higher oxidative stress may contribute to the pathogenesis of coronary artery disease (CAD). The purpose of this study was to investigate the relationship between coenzyme Q10 concentration and lipid peroxidation, antioxidant enzymes activities and the
Bor-Jen Lee+5 more
doaj +6 more sources
Effects of Oral, Vaginal, and Transdermal Hormonal Contraception on Serum Levels of Coenzyme Q10, Vitamin E, and Total Antioxidant Activity [PDF]
The use of the transdermal contraceptive patch is associated with greater bioavailability of ethinyl estradiol (EE) compared with contraceptive vaginal ring or oral contraceptives (OC).
Prabhudas R. Palan+4 more
doaj +4 more sources
Investigation of coenzyme Q10 status, serum amyloid-β, and tau protein in patients with dementia
ObjectivesDementia is an oxidative stress-related disease. Coenzyme Q10 is a nutrient that occurs naturally in the human body and acts as an antioxidant.
Po-Sheng Chang+10 more
doaj +1 more source
Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q10, to improve the dissolution and the oral bioavailability.
Thapa Chhitij+11 more
doaj +1 more source
Background AarF domain-containing kinase 4 (ADCK4)-associated glomerulopathy is a mitochondrial nephropathy caused by mutations in the ADCK4 gene, which disrupt coenzyme Q10 biosynthesis.
Yan Zhang+8 more
doaj +1 more source
The effects of coenzyme Q10 (CoQ10) on Ionizing radiation- induced pancreatic β-cell injury [PDF]
Objective: This study investigated the antioxidant effect of coenzyme Q10 on ionizing radiation induced oxidative damage in pancreatic & beta;-cells. Methods: Twenty-four male rats were assigned to 4 groups. Group 1 constituted the control group, Group 2
Mercantepe, Filiz+3 more
core +1 more source
Effects of ligand binding on the energy landscape of acyl-CoA-binding protein [PDF]
Binding of ligands is often crucial for function yet the effects of ligand binding on the mechanical stability and energy landscape of proteins are incompletely understood. Here we use a combination of single-molecule optical tweezers and MD simulations to investigate the effect of ligand binding on the energy landscape of acyl-coenzyme A (CoA) binding
arxiv +1 more source
Effect of iron and silver nanoparticles on coenzyme Q10 production by Gluconobacter japonicus FM10
Background and Objectives: Coenzyme Q10 is an anti-aging agent whose demand is increasing progressively. There are various strategies used for increasing coenzyme Q10 production by microorganisms.
Foozieh Moghadami, Ramin Hosseini
doaj +1 more source
Analysis and Suggestions of Evaluation and Approval for Health Foods Containing Coenzyme Q10
Coenzyme Q10 is a fat-soluble vitamin-like benzoquinone compound, which is synthesized endogenously from tyrosine in human body. It has many physiological functions, such as participating in ATP production capacity, scavenging free radicals and anti ...
Yu JIANG+4 more
doaj +1 more source
Prebiotic Vitamin B$_3$ Synthesis in Carbonaceous Planetesimals [PDF]
Aqueous chemistry within carbonaceous planetesimals is promising for synthesizing prebiotic organic matter essential to all life. Meteorites derived from these planetesimals delivered these life building blocks to the early Earth, potentially facilitating the origins of life.
arxiv +1 more source