Results 71 to 80 of about 1,272 (143)

Impurity-coformer cocrystals and/or complexes and their use in separations

, 2013
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Hsi, Kay Huai Ying
core  

Influence of Sodium Lauryl Sulfate and Tween 80 on Carbamazepine–Nicotinamide Cocrystal Solubility and Dissolution Behaviour

Pharmaceutics, 2013
The influence of the surfactants of sodium lauryl sulfate (SLS) and Tween 80 on carbamazepine–nicotinamide (CBZ–NIC) cocrystal solubility and dissolution behaviour has been studied in this work.
Ke Wang, Ning Qiao, Mingzhong Li
doaj   +1 more source

The natural bile acid surfactant sodium taurocholate (NaTC) as a coformer in coamorphous systems: Enhanced physical stability and dissolution behavior of coamorphous drug-NaTc systems

, 2018
The amorphization of 18 different drugs on milling with one mole equivalent sodium taurocholate (NaTC) was investigated. In all cases the X-ray powder pattern showed an amorphous halo after milling at room temperature or after cryomilling and 14 of the ...
Katarzyna Gniado, Pól MacFhionnghaile, Andrea Erxleben, Gniado, Katarzyna, Erxleben, Andrea, Patrick McArdle, MacFhionnghaile, Pól, McArdle, Patrick   +7 more
core   +1 more source

Compatible Transformer for Irregularly Sa: Multivariate Time Series

, 2023
To analyze multivariate tune series, most previous methods assume regular subsampling of tune series, where the interval between adjacent measurements and the number of samples remain unchanged.
Peng, J, He, T, Chen, S, Wei, Y, Xu, C, Zhang, J, Pan, S   +6 more
core   +1 more source

4-Nitrobenzoic acid–sulfathiazole (1/1)

Acta Crystallographica Section E, 2014
In the crystal structure of the title compound, C7H5NO4·C9H9N3O2S2, the sulfathiazole and 4-nitrobenzoic acid molecules are held together by short π–π contacts between the thiazole and nitrobenzene rings, with a centroid–centroid distance of 3.8226 (7) Å.
Madhavi Oruganti, Darshak R. Trivedi
doaj   +1 more source

Role of Coformer and Excipient Properties on the Solid-State Stability of Theophylline Cocrystals

, 2019
The stability of theophylline cocrystals composed of acidic (glutaric acid), basic (isonicotinamide), or neutral (benzamide) coformers was evaluated in the presence of several excipients.
Kapildev K. Arora, Joseph F. Krzyzaniak (2980530), Raj Suryanarayanan (1246851), Suman Luthra (4694719), Sampada Koranne, Raj Suryanarayanan, Suman Luthra, Joseph F. Krzyzaniak, Kapildev K. Arora (1298715), Sampada Koranne (3809611)   +9 more
core   +1 more source

Evaluation of Piperine as Natural Coformer for Eutectics Preparation of Drugs Used in the Treatment of Cardiovascular Diseases

, 2022
Piperine (PIP) was evaluated as a natural coformer in the preparation of multicomponent organic materials for enhancing solubility and dissolution rate of the poorly water-soluble drugs: curcumin (CUR), lovastatin (LOV), and irbesartan (IBS). A screening
Quirós-Fallas, MI, Jose-Roberto, Vega-Baudrit, Guillen-Girón, Teodolito, Navarro-Hoyos, Mirtha, Araya Sibaja, Andrea Mariela, Vargas-Huertas, Felipe, Wilhelm-Romero, K   +6 more
core   +1 more source

Non-Covalent Derivatives: Cocrystals and Eutectics

Molecules, 2015
Non-covalent derivatives (NCDs) are formed by incorporating one (or more) coformer molecule(s) into the matrix of a parent molecule via non-covalent forces.
Emily Stoler, John C. Warner
doaj   +1 more source

Crystal Engineering of Nevirapine for Improved Dissolution Characteristics: An Interesting Behavior of a Coformer During Evaporative Cocrystallization

, 2022
   In this work, we report the synthesis of a new eutectic and a cocrystal phases of Nevirapine (NEV), a Biopharmaceutics Classification System (BCS) class II antiretroviral drug with enhanced dissolution. NEV with paracetamol (PAR) formed an eutectic at
Indumathi Sathisaran (4090099), Sameer Vishvanath Dalvi (1628503)   +1 more
core   +1 more source

Salts and Cocrystals of the Antidiabetic Drugs Gliclazide, Tolbutamide, and Glipizide: Solubility Enhancements through Drug Coformer Interactions

, 2017
Gliclazide (GCZ), tolbutamide (TOL), and glipizide (GPZ) are BCS class II antidiabetic drugs with poor aqueous solubility. Multicomponent solid forms, salts, and cocrystals of GCZ were obtained upon liquid assisted grinding with coformers of catechol ...
Manas Banik, Desiraju, Gautam R, Gautam R. Desiraju, Banik, Manas, Samie, Ali, Ali Samie   +5 more
core   +1 more source