Results 101 to 110 of about 14,462 (190)

The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome

Clinical Epigenetics, 2017
Background Cornelia de Lange syndrome (CdLS) is a multisystem developmental disorder frequently associated with heterozygous loss-of-function mutations of Nipped-B-like (NIPBL), the human homolog of Drosophila Nipped-B. NIPBL loads cohesin onto chromatin.
Daniel A. Newkirk, Yen-Yun Chen, Richard Chien, Weihua Zeng, Jacob Biesinger, Ebony Flowers, Shimako Kawauchi, Rosaysela Santos, Anne L. Calof, Arthur D. Lander, Xiaohui Xie, Kyoko Yokomori   +11 more
doaj   +1 more source

The kinetochore is an enhancer of pericentric cohesin binding.

PLoS Biology, 2004
The recruitment of cohesins to pericentric chromatin in some organisms appears to require heterochromatin associated with repetitive DNA. However, neocentromeres and budding yeast centromeres lack flanking repetitive DNA, indicating that cohesin ...
Stewart A Weber, Jennifer L Gerton, Joan E Polancic, Joseph L DeRisi, Douglas Koshland, Paul C Megee   +5 more
doaj   +1 more source

Cohesin is required for activation of MYC by estradiol.

PLoS ONE, 2012
Cohesin is best known as a multi-subunit protein complex that holds together replicated sister chromatids from S phase until G2. Cohesin also has an important role in the regulation of gene expression.
Miranda V McEwan, Michael R Eccles, Julia A Horsfield   +2 more
doaj   +1 more source

Different loading requirements of cohesin-STAG1 and cohesin-STAG2

, 2023
Tesis Doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular.
openaire   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Genetic basis of cohesinopathies

The Application of Clinical Genetics, 2013
José L Barbero Cellular and Molecular Biology Department, Biological Research Center, Madrid, Spain Abstract: Cohesin is a ring-form multifunctional protein complex, which was discovered during a search for molecules that keep sister chromatids ...
Barbero JL
doaj  

Cohesin and condensin regulate chromosome topology and play an essential role in maintaining pluripotency in embryonic stem cells

Scientific Reports
Cohesin and condensin, two related protein complexes, play essential roles in ensuring the accurate segregation of the genome into daughter cells during cell division. However, the interaction between cohesin and condensin in embryonic stem cells remains
Eui-Hwan Choi, Keun P. Kim
doaj   +1 more source

RNAPII and DNA supercoiling regulate cohesin engagement in neurons. [PDF]

Nucleic Acids Res
Crewe M, Delint-Ramirez I, Halawa O, Heady L, Madabhushi R.   +4 more
europepmc   +1 more source

Cohesin-mediated loop extrusion and enhancer-associated factors additively contribute to <i>Sox2</i> looping with its distal enhancer. [PDF]

Genes Dev
Martinovic M, Flach KD, de Kort MAC, Maresca M, Teunissen H, Liu NQ, Lenstra TL, de Wit E.   +7 more
europepmc   +1 more source