Results 71 to 80 of about 4,211 (161)

Contribution of colibactin-producing Escherichia coli to colonic carcinogenesis. [PDF]

eGastroenterology
Ishikawa H, Aoki R, Mutoh M, Ishiguro S, Tanaka T, Miyoshi N, Miyamoto S, Hamoya T, Yoshida N, Wakabayashi K, Watanabe K.   +10 more
europepmc   +4 more sources

Gut Microbiota: A Reservoir for Extraintestinal Bacterial Infections in Febrile Term Infants

iLABMED, Volume 4, Issue 2, Page 116-119, June 2026.
Ran Wang, Renqiang Yu
wiley   +1 more source

Molecular Genetic and Functional Analysis of pks-Harboring, Extra-Intestinal Pathogenic Escherichia coli From India

Frontiers in Microbiology, 2018
Colibactin, a genotoxin, encoded by the pks pathogenicity island of Escherichia coli belonging to the B2 phylogroup has been reported as a determinant of bacterial pathogenicity. The present study was carried out to detect the pks pathogenicity island in
Arya Suresh, Amit Ranjan, Savita Jadhav, Arif Hussain, Sabiha Shaik, Munirul Alam, Ramani Baddam, Lothar H. Wieler, Niyaz Ahmed, Niyaz Ahmed   +9 more
doaj   +1 more source

Increased Epithelial Oxygenation Links Colitis to an Expansion of Tumorigenic Bacteria

mBio, 2019
Intestinal inflammation is a risk factor for colorectal cancer formation, but the underlying mechanisms remain unknown. Here, we investigated whether colitis alters the colonic microbiota to enhance its cancer-inducing activity.
Stephanie A. Cevallos, Jee-Yon Lee, Connor R. Tiffany, Austin J. Byndloss, Luana Johnston, Mariana X. Byndloss, Andreas J. Bäumler   +6 more
doaj   +1 more source

INTERMICROBIAL «SELF-NON-SELF» DISCRIMINATION IN «DOMINANT-ASSO-CIANT» PAIR OF PROBIOTIC STRAINS OF ESCHERICHIA COLI M-17 AND E.COLI LEGM-18

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. To use earlier developed method of intermicrobial «self-non-self» discrimination in «dominant-associant» pair for the assessment of foreignness of probiotic cultures of Escherichia coli M-17 (with pathogenicity island) and E.
O. V. Bukharin, N. B. Perunova, E. V. Ivanova, S. V. Andryuschenko   +3 more
doaj   +1 more source

Determining the Sequence of Two Colibactin Genes, clbN and clbB, in Some Clinical Isolates of E. coli

Medical Journal of Babylon
Background: Escherichia coli is a widespread human-infecting bacterium that can produce the genotoxin colibactin, which is encoded by the pks pathogenicity island and has been reported as a determinant of bacterial virulence.
Noor Ismeal Nasser, Mohammed Sabri Abdul-Razzag, Nadia Mudher AL-Hili   +2 more
doaj   +1 more source

Contribution of pks+ Escherichia coli (E. coli) to Colon Carcinogenesis

Microorganisms
Colorectal cancer (CRC) stands as a significant global health concern, ranking second in mortality and third in frequency among cancers worldwide. While only a small fraction of CRC cases can be attributed to inherited genetic mutations, the majority ...
Mohammad Sadeghi, Denis Mestivier, Iradj Sobhani   +2 more
doaj   +1 more source

Enrichment of colibactin-associated mutational signatures in unexplained colorectal polyposis patients

BMC Cancer
Background Colibactin, a genotoxin produced by polyketide synthase harboring (pks + ) bacteria, induces double-strand breaks and chromosome aberrations.
Diantha Terlouw, Arnoud Boot, Quinten R. Ducarmon, Sam Nooij, Manon Suerink, Monique E. van Leerdam, Demi van Egmond, Carli M. Tops, Romy D. Zwittink, Dina Ruano, Alexandra M. J. Langers, Maartje Nielsen, Tom van Wezel, Hans Morreau   +13 more
doaj   +1 more source

Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917.

PLoS Pathogens, 2019
Although Escherichia coli Nissle 1917 (EcN) has been used therapeutically for over a century, the determinants of its probiotic properties remain elusive. EcN produces two siderophore-microcins (Mcc) responsible for an antagonistic activity against other
Clémence Massip, Priscilla Branchu, Nadège Bossuet-Greif, Camille V Chagneau, Déborah Gaillard, Patricia Martin, Michèle Boury, Thomas Sécher, Damien Dubois, Jean-Philippe Nougayrède, Eric Oswald   +10 more
doaj   +1 more source

Colibactin comes to light [PDF]

Nature Chemical Biology, 2019
openaire   +2 more sources