Results 81 to 90 of about 4,211 (161)

Macrocyclic colibactins

Nature Chemistry, 2020
openaire   +3 more sources

Colibactin-producing Escherichia coli enhance resistance to chemotherapeutic drugs by promoting epithelial to mesenchymal transition and cancer stem cell emergence

Gut Microbes
Human colorectal cancers (CRCs) are readily colonized by colibactin-producing E. coli (CoPEC). CoPEC induces DNA double-strand breaks, DNA mutations, genomic instability, and cellular senescence.
Guillaume Dalmasso, Antony Cougnoux, Tiphanie Faïs, Virginie Bonnin, Benoit Mottet-Auselo, Hang TT Nguyen, Pierre Sauvanet, Nicolas Barnich, Marine Jary, Denis Pezet, Julien Delmas, Richard Bonnet   +11 more
doaj   +1 more source

Campylobacter jejuni infection impacts host-derived miRNAs targeting bacterial and host genes

Microbiology Spectrum
The intestinal microbiota has been shown to influence host-derived microRNAs (miRNAs), small regulatory RNAs involved in host-pathogen interactions. However, the specific role of individual bacterial species in modulating host extracellular vesicles (EV)-
Siddhi Chitre, Raad Z. Gharaibeh, Rachel C. Newsome, Jinmai Jiang, Andrew Brock, Thomas D. Schmittgen, Christian Jobin   +6 more
doaj   +1 more source

Study of colibactin in urinary tract infections

, 2021
Urinary tract infections (UTIs) are among the most common community-acquired or nosocomial bacterial infections. They are most often caused by uropathogenic Escherichia coli (UPECs). We assembled a collection of UPECs from 223 patients suffering from community-acquired UTIs in order to understand the role and impact of potential virulence factors of ...
openaire   +1 more source

From inflammation to fibrosis and cancer: the emerging role of AIEC-derived metabolites in intestinal disease progression. [PDF]

Exp Mol Med
Ahn JH, Hazelton A, Nguyen J, Arthur JC.
europepmc   +1 more source

Prevalence and Molecular Characteristics of Klebsiella pneumoniae Harboring the Pks Island from Cancer Patients in China

Infection and Drug Resistance
Qun Wang,1 Xingwei Wang,2 Zhenghua Xie,1 Jiuxin Qu,2 Yongping Lin,1 Jing Hu,3 Liqiang Li,2 Li Zhang1 1National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and ...
Wang Q, Wang X, Xie Z, Qu J, Lin Y, Hu J, Li L, Zhang L   +7 more
doaj  

Isolation of a highly virulent colibactin-positive tumor-promoting strain of <i>Escherichia coli</i> from the gut microbiota of an adult. [PDF]

mSphere
Weis AM, Matthews OJ, Bell R, Pershing NL, Dankwardt A, Fleming BA, Gigic B, Schneider M, Hardikar S, Toriola AT, Shibata D, Li CI, Byrd DA, Stephens WZ, Ulrich CM, Mulvey MA, Round JL.   +16 more
europepmc   +1 more source

Microbiomics: Novel Biomarkers of Colorectal Cancer Diagnosis and Prognosis. [PDF]

Diagnostics (Basel)
Yang L, Meng W, Yang T, Zhu Y, Wang Z.
europepmc   +1 more source

Colibactin genes are highly prevalent in the developing infant gut microbiome. [PDF]

Gut Microbes
Levy S, McCauley KE, Strength R, Robbins ES, Chen Q, Namasivyam S, Maxwell G, Hourigan SK.   +7 more
europepmc   +1 more source

Genomic evidence of convergence of multidrug resistance and enhanced virulence in carbapenem- and colistin-resistant <i>Klebsiella pneumoniae</i> from Turkey. [PDF]

Microbiol Spectr
Rafei R, Kassem II, Abbass H, Ghorbani Tajani A, Baroudi A, Hassan J, Dabboussi F, Doğan M, Hamze M, Ericson JE, Schiff SJ, Bisha B, Özdemir M, Osman M.   +13 more
europepmc   +1 more source