Association of Chondroadherin with Collagen Type II [PDF]
Journal of Biological Chemistry, 2001 Chondroadherin is a cell binding, leucine-rich repeat protein found in the territorial matrix of articular cartilage. Several members of the leucine-rich repeat protein family present in the extracellular matrix of e.g. cartilage have been shown to interact with collagen and influence collagen fibrillogenesis.
B, Mansson +4 more
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High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II. [PDF]
Sci Adv, 2021 Fibronectin binding to collagen type II is crucial for articular chondrocytes to stay in a healthy steady state.
van Hoolwerff M +10 more
europepmc +2 more sources
Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin β1-SMAD1 interaction. [PDF]
Bone Res, 2019 Hypertrophic differentiation is not only the terminal process of endochondral ossification in the growth plate but is also an important pathological change in osteoarthritic cartilage.
Lian C +14 more
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Glycosaminoglycans from bovine eye vitreous humour and interaction with collagen type II. [PDF]
Glycoconj J, 2018 Glycosaminoglycans (GAGs) play an important role in stabilizing the gel state of eye vitreous humour. In this study, the composition of GAGs present in bovine eye vitreous was characterized through disaccharide analysis by liquid chromatography-mass ...
Peng Y +9 more
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Collagen Type II enhances chondrogenic differentiation in agarose-based modular microtissues. [PDF]
Cytotherapy, 2016 Tiruvannamalai Annamalai R +3 more
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Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells. [PDF]
Mol Med Rep, 2017 Degenerative disc disease (DDD) is a common degenerative condition initiated mainly within the nucleus pulposus (NP). To date, the etiopathogenesis of DDD remains unclear, and because no effective therapeutic strategies are available to target its ...
Lian C +8 more
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Engineering zonal cartilage through bioprinting collagen type II hydrogel constructs with biomimetic chondrocyte density gradient. [PDF]
BMC Musculoskelet Disord, 2016 BackgroundCartilage tissue engineering is a promising approach for repairing and regenerating cartilage tissue. To date, attempts have been made to construct zonal cartilage that mimics the cartilaginous matrix in different zones.
Ren X +5 more
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Type II collagen distribution in rodents [PDF]
The Laryngoscope, 1988 AbstractThe anatomical distribution of type II collagen in animal ears was studied by immunohistochemical techniques, using defined monoclonal antibodies to type II collagen.Type II collagen was observed in the cartilage plate of the auricle and external auditory meatus, tympanic annulus, lamina propria of tympanic membrane (pars tensa), interossicular
T J, Yoo, K, Tomoda
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Characterization of the T cell receptor repertoire causing collagen arthritis in mice [PDF]
, 1993 Collagen type II-induced arthritis (CIA) is generated in susceptible rodent strains by intradermal injections of homologous or heterologous native type II collagen in complete Freund's adjuvant.
Hood, Leroy E. +3 more
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Marine Drugs, 2019 The composition and properties of collagen in teleost (bony fish) cartilage have never been studied. In this study, we aimed to identify and characterise all collagen species in the nasal cartilage of hoki (Macruronus novaezelandiae).
Mathew H. Cumming +2 more
doaj +1 more source