Results 91 to 100 of about 7,552,757 (294)

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

open access: yesAdvanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos   +17 more
wiley   +1 more source

IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics [PDF]

open access: yes, 2016
Systemic sclerosis is an autoimmune connective tissue disease in which T cells play a prominent role. We and others have previously demonstrated a role for T cell-derived IL-13 in mediating the induction of collagen in dermal fibroblasts and that ...
van Laar, Jacob   +10 more
core   +2 more sources

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao   +9 more
wiley   +1 more source

Normal and Gene-Corrected Dystrophic Epidermolysis Bullosa Fibroblasts Alone Can Produce Type VII Collagen at the Basement Membrane Zone [PDF]

open access: yes, 2003
Type VII collagen is synthesized and secreted by both human keratinocytes and fibroblasts. Although both cell types can secrete type VII collagen, it is thought that keratinocytes account for type VII collagen at the dermal–epidermal junction (DEJ).
Atha, Tom   +8 more
core   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

open access: yesAdvanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang   +9 more
wiley   +1 more source

Type VII Collagen, Anchoring Fibrils, and Epidermolysis Bullosa

open access: yesJournal of Investigative Dermatology, 1993
The anchoring fibrils at the dermal-epidermal junction have been well characterized as ultrastructural entities. From their appearance, it was proposed that they fortified the attachment of the epidermis to the dermis. This hypothesized function was strengthened by observations indicating that the anchoring fibrils were abnormal, diminished, or absent ...
openaire   +2 more sources

The tissue form of type VII collagen is an antiparallel dimer.

open access: yesJournal of Biological Chemistry, 1986
We recently reported the partial characterization of a new human collagen termed Type VII. This molecule is distinctive among the collagen family in that it contains three identical subunit alpha chains within a triple helical domain 424 nm in length.
N P, Morris   +4 more
openaire   +2 more sources

Anchoring Fibrils and Type VII collagen are Absent From Skin in Severe Recessive Dystrophic Epidermolysis Bullosa [PDF]

open access: yes, 1989
Skin of patients with severe generalized recessive dystrophic epidermolysis bullosa (SGRDEB) was studied by immunoelectron microscopy and immunoblotting with antibodies to type VII collagen, a major structural component of anchoring fibrils.
Bruckner, Peter   +3 more
core   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

open access: yesAdvanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li   +7 more
wiley   +1 more source

MORPHOLOGICAL CHARACTERISTICS OF CORONARY AND CAROTID ATHEROSCLEROTIC PLAQUES IN PATIENTS WITH MYOCARDIAL INFARCTION

open access: yesНаука и инновации в медицине, 2017
Aim - to study the correlation between the thickness of the fibrous cap and collagen in the coronary and carotid plaques in patients with myocardial infarction. Materials and methods.
LN N Slatova   +4 more
doaj   +1 more source

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