Results 31 to 40 of about 33,936 (220)

Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells [PDF]

, 2023
Colorectal cancer (CRC) is a significant global health burden with a rising incidence worldwide. Distinct bacterial populations are associated with CRC development and progression, and it is thought that the relationship between CRC and associated gut ...
Collard, T. J., Thorn, R. M. S., Qualtrough, D., Robson, J. L., Williams, A. C.   +4 more
core   +1 more source

LPS Induces microRNAs -9, -192, and -205 Overexpression in Colorectal Cell Lines SW480, HCT116

Middle East Journal of Cancer, 2020
Background: Today, cancer is one of the serious health issues worldwide. In USA, colorectal cancer is the third cause of death. Reportedly, some risk factors, including family history of colorectal cancer, age, and infectious diseases can deteriorate the
Shaian Tavakolian, Hossein Goudarzi, Ebrahim Faghihloo   +2 more
doaj   +1 more source

Hedyotis diffusa–Sculellaria barbata (HD–SB) suppresses the progression of colorectal cancer cells via the hsa_circ_0039933/hsa-miR-204-5p/wnt11 axis

Scientific Reports, 2023
Our previous study confirmed that the combination of Hedyotis diffusa (HD) and Scutellaria barbata (SB) significantly inhibited colorectal cancer cell proliferation and the WNT signaling pathway.
Danye Zhu, Shanmin Yuan, Cong Chen
doaj   +1 more source

Investigation of the Cytotoxic and Antiproliferative Effects of Liposomal Daunorubicin on Human Colorectal Cancer (HCT116) Cell Line. [PDF]

Iran J Pharm Res
Background: The incidence of colorectal cancer is increasing globally. Daunorubicin (DNR), an anthracycline antibiotic, is effective against various cancers. The PI3K/AKT/mTOR signaling pathway is crucial in regulating cell growth and cancer growth.
Alaa Hadi-Al-Ward N, Ebrahimi M, Zare Karizi S.   +2 more
europepmc   +3 more sources

Downregulation of miR-423-5p Contributes to the Radioresistance in Colorectal Cancer Cells

Frontiers in Oncology, 2021
Resistance to radiotherapy is the main reason causing treatment failure in locally advanced rectal cancer. MicroRNAs (miRNAs) have been well demonstrated to regulate cancer development and progression. However, how miRNAs regulate radiotherapy resistance
Yuanyuan Shang, Lingfei Wang, Zhe Zhu, Wei Gao, Dan Li, Zhuqing Zhou, Lin Chen, Chuan-gang Fu   +7 more
doaj   +1 more source

Genotoxicity and oxidative stress induction by polystyrene nanoparticles in the colorectal cancer cell line HCT116

PLOS ONE, 2021
The potential risks of environmental nanoparticles (NPs), in particular Polystyrene Nanoparticles (PNPs), is an emerging problem; specifically, the interaction of PNPs with intestinal cells has not been characterized so far. The mechanism by which polystyrene particles are transferred to humans has not yet been clarified, whether directly through ...
Giulia Vecchiotti, Sabrina Colafarina, Massimo Aloisi, Osvaldo Zarivi, Piero Di Carlo, Anna Poma   +5 more
openaire   +6 more sources

Expression of γ-synuclein in colorectal cancer tissues and its role on colorectal cancer cell line HCT116

World Journal of Gastroenterology, 2009
To investigate the expression pattern of gamma-synuclein in colorectal cancer (CRC) tissues, and to study the effects of gamma-synuclein on CRC cell line HCT116 biological features in vitro.The expression pattern of gamma-synuclein was determined in 54 CRC tissues and 30 tumor-matched nonneoplastic adjacent tissues (NNAT) 5 cm away from the tumor via ...
Qing, Ye, Bo, Feng, Yuan-Fei, Peng, Xue-Hua, Chen, Qu, Cai, Bei-Qin, Yu, Liang-Hui, Li, Ming-Yuan, Qiu, Bing-Ya, Liu, Min-Hua, Zheng   +9 more
openaire   +2 more sources

Generation of a cancer testis antigen mCherry reporter HCT116 colorectal carcinoma cell line [PDF]

Heliyon, 2018
In the context of cancer immunotherapy, agents that target the immune system to cancer cells need to fulfil two criteria: 1) that they are only expressed on the desired target cell and 2) that they can elicit a potent immunological response. Cancer Testis Antigens are a large disparate family of factors ordinarily expressed in the germ-line but ...
Jyoti B. Chhetri, Elena Drousioti, José Afonso Guerra-Assunção, Javier Herrero, Steen K.T. Ooi   +4 more
openaire   +4 more sources

Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade [PDF]

, 2012
Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and ...
Prem Kumar, Sutherland K Maciver, Manuel Salto-tellez, Celestial T. Yap (142210), Tochhawng, L., Zhuo, J., Celestial T Yap, Maciver, S.K., Koh, Shiuan, K. Maciver, Salto-Tellez Manuel, Manikandan Jayapal (64624), Tan, Ee Hong, Hooi, S., Jayapal, Manikandan, Maciver, Sutherland K., Yaw Chyn Lim (142208), Zhuo Jingli, Lalchhandami Tochhawng (142188), Jingli Zhuo, Ee Hong Tan (142182), Ee Hong Tan, Alan Prem Kumar (142201), Tay Hwee Kee, Lim, Yaw Chyn, Tay, H., Kumar, A.P., Tochhawng, Lalchhandami, Alan Prem Kumar, Maciver, Sutherland K, Ami Tochhawng, Koh, S., Salto-Tellez, M., Hwee Kee Tay (64625), Tay, H.K., Maciver, S., Benedict Yan (142185), Yap Celestial T., Kumar, Alan Prem, Shiuan Koh (142191), Lalchhandami Tochhawng, Lim, Y., Shing Chuan Hooi (50996), Jayapal Manikandan, Goh, Yaw Chong, Shiuan Koh, Tan, E.H., Yap, C., Yap, Celestial T, Yap, Celestial T., Tochhawng Lalchhandami, Tan, E., Lim, Y.C., Hooi, Shing Chuan, An Jayapal, Yan, B., Hwee Kee Tay, Hooi, S.C., Kumar Alan Prem, Sutherland K. Maciver (142194), Tan Ee Hong, Celestial T. Yap, Goh, Y., Manikandan Jayapal, Maciver Sutherland K., Goh Yaw Chong, Jingli Zhuo (142178), Zhuo, Jingli, Yap, C.T., Benedict Yan, Lim Yaw Chyn, Yan, Benedict, Jayapal, M., Yaw Chyn Lim, Goh, Y.C., Salto-Tellez, Manuel, Yaw Chong Goh, Yaw Chong Goh (142205), Koh Shiuan, Yan Benedict, Hooi Shing Chuan, Manuel Salto-Tellez (142198), Tay, Hwee Kee, Shing Chuan Hooi   +83 more
core   +1 more source

Salinomycin Triggers Human Colorectal Cancer HCT116 Cell Death by Targeting Unfolded Protein Responses and Autophagy Pathways [PDF]

, 2023
Background: Autophagy and the unfolded protein response (UPR) are important pathways in colorectal tumorigenesis and drug resistance, rendering them as potential therapeutic targets for treating this cancer.
Pooneh Mokarram, Mozhdeh Zamani, Morvarid Siri, Sanaz Dastghaib   +3 more
core   +1 more source