Results 71 to 80 of about 33,936 (220)
Identificació de nous marcadors moleculars en metàstasi hepàtica de càncer colorectal [PDF]
, 2010 [cat] L’objectiu d’aquest treball és la identificació i caracterització de les principals alteracions en metàstasi hepàtica (MH) de càncer colorectal (CCR) tant a nivell d’expressió gènica com de metilació de l’ADN.
Padullés Mosella, Laura
core
, 2017 Colorectal cancer (CRC) is the third leading cause of malignant mortality worldwide, accounting for more than 13% of all cancer death. CRC harbors several alterations, mainly, two major classes of these instability were described: 1/microsatellite ...
Jean-Pierre Roperch +4 more
core +1 more source
Expression of MOB3B in colorectal cancer and its relationship with survival prognosis
, 2023 [Objectives] To investigate the expression of MOB3B in colorectal cancer and its relationship with survival prognosis. [Methods] The expression of MOB3B in colorectal cancer and adjacent normal tissues, and its relationship with survival prognosis was ...
Wu Qingru +8 more
core +1 more source
Advanced Science, EarlyView.Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
MiR-483-3p regulates oxaliplatin resistance by targeting FAM171B in human colorectal cancer cells
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Oxaliplatin resistance limits the efficiency of treatment for colorectal cancer (CRC). Studies have shown that abnormal expression of microRNAs (miRNAs) were associated with tumorigenesis, cancer development and chemoresistance. The purpose of this study
Hui Liang +8 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao +12 more
wiley +1 more source
The Pro-Apoptotic Effects of Curcumin on HCT116 Colorectal Cancer Cells
Midwestern Journal of Undergraduate SciencesColorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide, often originating from benign polyps in the colon and rectum that may become malignant if left untreated. While current treatments such as surgery, chemotherapy, and radiation are effective, they often come with severe side effects that impact patient quality of ...
Kuljeet Kaur +3 more
openaire +1 more source
Results in ChemistryColorectal cancer (CRC) is one of the most common and deadly cancers worldwide and drug resistance of chemotherapy pose a great challenge to the treatment for CRC.
Yuqi Yue +9 more
doaj +1 more source
AntiGan: An Epinutraceutical Bioproduct with Antitumor Properties in Cultured Cell Lines
Life, 2022 Novel and effective chemotherapeutic agents are needed to improve cancer treatment. Epidrugs are currently used for cancer therapy but also exhibit toxicity. Targeting the epigenetic apparatus with bioproducts may aid cancer prevention and treatment.
Olaia Martínez-Iglesias +3 more
doaj +1 more source
Advanced Science, EarlyView.The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang +23 more
wiley +1 more source