Results 41 to 50 of about 1,956,113 (201)
Relationship between CpG and non-CpG DNA methylation in human lymphocytes assessed with comet assay [PDF]
The Ukrainian Biochemical JournalTissue-specific DNA methylation plays an important role in the regulation of many functional processes. The methylation level in single cells can be assessed using the comet assay (single-cell gel electrophoresis), a simple and cost-effective technique ...
M. Chopei +3 more
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Mutagenesis, 2018 Metallic nanoparticles (NPs) are promising nanomaterials used in different technological solutions as well as in consumer products. Silver (Ag), gold (Au) and platinum (Pt) represent three metallic NPs with current or suggested use in different ...
J. Lebedová +3 more
semanticscholar +1 more source
The comet assay – from toy to tool
Frontiers in Genetics, 2015 The comet assay is nowadays the most common method for measuring DNA damage and repair in single cells. It is based on the microelectrophoretic study published by Ostling and Johanson (1984) and was developed by Singh and coworkers (1988) to a versatile ...
Guenter Speit
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Protective effects of phenolic acids on mercury-induced DNA damage in precision-cut kidney slices [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Precision-cut tissue slices are considered an organotypic 3D model widely used in biomedical research. The comet assay is an important screening test for early genotoxicity risk assessment that is mainly applied on in vitro models. The aim
Irma Edith Carranza-Torres +7 more
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Comet assay on mice testicular cells
Frontiers in Genetics, 2015 Heritable mutations may result in a variety of adverse outcomes including genetic disease in the offspring. In recent years the focus on germ cell mutagenicity has increased and the “Globally Harmonized System of Classification and Labelling of ...
Anoop Kumar Sharma
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Evaluation of the Major Steps in the Conventional Protocol for the Alkaline Comet Assay
International Journal of Molecular Sciences, 2019 Single cell gel electrophoresis, also known as the comet assay, has become a widespread DNA damage assessment tool due to its sensitivity, adaptability, low cost, ease of use, and reliability.
M. Karbaschi +8 more
semanticscholar +1 more source
The Comet Assay as a Tool to Detect the Genotoxic Potential of Nanomaterials
Nanomaterials, 2019 The interesting physicochemical characteristics of nanomaterials (NMs) has brought about their increasing use and, consequently, their increasing presence in the environment.
A. García-Rodríguez +6 more
semanticscholar +1 more source
Controlling variation in the comet assay
Frontiers in Genetics, 2014 Variability of the comet assay is a serious issue, whether it occurs from experiment to experiment in the same laboratory, or between different laboratories analysing identical samples.
Andrew Richard Collins +5 more
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Epithelial cells as alternative human biomatrices for comet assay
Frontiers in Genetics, 2014 The comet assay is a valuable experimental tool aimed at mapping DNA damage in human cells in vivo for environmental and occupational monitoring, as well as for therapeutic purposes, such as storage prior to transplant, during tissue engineering, and in ...
Emilio eRojas +4 more
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The Effect of Obstructive Sleep Apnea on DNA Damage and Oxidative Stress [PDF]
Clinical and Experimental Otorhinolaryngology, 2013 ObjectivesObstructive sleep apnea syndrome (OSAS) is associated with repeated hypoxia and re-oxygenation. This characteristic of OSAS may cause oxidative stress and DNA damage.
Il Gyu Kang, Joo Hyun Jung, Seon Tae Kim
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