Results 61 to 70 of about 173,661,164 (297)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Introduction to the Community of Inquiry theoretical framework

open access: yes
This chapter introduces this book and the Community of Inquiry theoretical framework that underlies the pedagogical applications described in it. We provide an overview of the learning settings described as communities of inquiry.
Stenbom, Stefan,   +1 more
core   +1 more source

Employing a Community of Inquiry Framework to Understand Graduate Students' Perceptions of Supports in Asynchronous Online Courses Focused on Assessment

open access: yesJournal of Human Services: Training, Research, and Practice, 2019
As universities increase the number of online course offerings, the quality of programs is often called into question. In many instances, student input is not solicited when devising online course offerings and faculty often lack the training needed to ...
Jessica A. Rueter   +2 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Using appreciative inquiry to explore the professional practice of a lecturer in higher education: moving towards life-centric practice [PDF]

open access: yes, 2010
This paper reports on a strategy for exploring the life-centric practice of a lecturer in Higher Education. The initiative for this inquiry arose out of the realisation that there did not appear to be positive, heart-lifting stories in a lecturer’s ...
Kung, Susie   +2 more
core  

The role of directive moral teaching: Reply to Michael Hand’s ‘Moral education in the community of inquiry’

open access: yesJournal of Philosophy in Schools, 2020
In this commentary on Michael Hand’s paper ’Moral education in the community of inquiry’, I argue that Hand is right to call for the Community of Inquiry method to include directive moral teaching.
Sue Knight
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Community Inquiry Labs as Effective Community Informatics Tools [PDF]

open access: yes, 2004
Meeting these challenges is crucial as we work to address community aspirations, capabilities, and problems. We are contributing to this effort through our current research and development on Community Inquiry Labs (CILs).
Palmer, Brent   +11 more
core  

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