Results 71 to 80 of about 1,209,417 (298)

Primary Sources in K–12 Education: Opportunities for Archives [PDF]

open access: yes, 2007
Recent developments in the field of K–12 (kindergarten through twelfth grade) education have made archival resources essential tools for many teachers. Inquiry-based learning, document-based questions, and high stakes standardized testing have converged ...
Hendry, Julia
core   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Leadership Development for Community Action: An Ethnographic Inquiry: Northwest Federation of Community Organizations [PDF]

open access: yes, 2005
LeeAnn Hall directs the Northwest Federation of Community Organizations (NWFCO), a collaboration of four state-based community organizations engaged in the fight for social and economic justice. Leadership development is at the heart of the NWFCO mission
Lisa Weinberg
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Shaping Pre-Service Teachers\u27 Attitudes: An Inquiry Approach to Course Reform [PDF]

open access: yes, 2000
The purpose of the study was to investigate the development of pre-service teachers’ attitudes toward teaching science with inquiry methods as the result of their participation in the two-hour elementary science methods class. Southwestern Oklahoma State
Campbell, B.   +2 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

A Microservice Infrastructure for Distributed Communities of Practice [PDF]

open access: yes, 2018
Non-formal learning in Communities of Practice (CoPs) makes up a significant portion of today’s knowledge gain. However, only little technological support is tailored specifically towards CoPs and their particular strengths and challenges.
AR Hevner   +13 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

The role of directive moral teaching: Reply to Michael Hand’s ‘Moral education in the community of inquiry’

open access: yesJournal of Philosophy in Schools, 2020
In this commentary on Michael Hand’s paper ’Moral education in the community of inquiry’, I argue that Hand is right to call for the Community of Inquiry method to include directive moral teaching.
Sue Knight
doaj   +1 more source

Learning mathematics in a classroom community of inquiry [PDF]

open access: yes, 2004
This article considers the question of what specific actions a teacher might take to create a culture of inquiry in a secondary school mathematics classroom.
Goos, M.
core   +1 more source

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