Results 1 to 10 of about 427,983 (270)

Urine complement analysis implies complement activation is involved in membranous nephropathy [PDF]

Frontiers in Medicine
BackgroundThe onset and progression of membranous nephropathy (MN) have been associated with complement activation, yet the overall characteristics of this activation in the kidneys remain unclear.
Yingxue Xu, Yingxue Xu, Yi Li, Yong Zhang, Guisen Li, Guisen Li   +5 more
doaj   +2 more sources

Complement activation in wasp venom-induced acute kidney injury [PDF]

Renal Failure
Previous studies have highlighted the significant role of complement activation in kidney injuries induced by rhabdomyolysis, intravascular hemolysis, sepsis, and ischemia-reperfusion.
Rui Cheng, Liang Xu, Jianhua Gong, Fanglin Yu, Ying Lv, Hai Yuan, Fengqi Hu   +6 more
doaj   +2 more sources

Complement Activation in Nephrotic Glomerular Diseases [PDF]

Biomedicines
The nephrotic syndrome holds significant clinical importance and is characterized by a substantial protein loss in the urine. Damage to the glomerular basement membrane or podocytes frequently underlies renal protein loss.
Dominik Nell, Robert Wolf, Przemyslaw Marek Podgorny, Tobias Kuschnereit, Rieke Kuschnereit, Thomas Dabers, Sylvia Stracke, Tilman Schmidt   +7 more
doaj   +2 more sources

Atypical Hemolytic Uremic Syndrome-Associated FHR1 Isoform FHR1*B Enhances Complement Activation and Inflammation

Frontiers in Immunology, 2022
Atypical hemolytic uremic syndrome (aHUS) is a rare but severe type of thrombotic microangiopathy that is triggered by the abnormal activation of the alternative complement pathway.
Boyang Xu, Yuqi Kang, Yujing Du, Weiyi Guo, Li Zhu, Hong Zhang   +5 more
doaj   +1 more source

Inside-Out of Complement in Cancer

Frontiers in Immunology, 2022
The role of complement in cancer has received increasing attention over the last decade. Recent studies provide compelling evidence that complement accelerates cancer progression.
Martin Kolev, Madhumita Das, Monica Gerber, Scott Baver, Pascal Deschatelets, Maciej M. Markiewski   +5 more
doaj   +1 more source

Factors affecting IgG4-mediated complement activation

Frontiers in Immunology, 2023
Of the four human immunoglobulin G (IgG) subclasses, IgG4 is considered the least inflammatory, in part because it poorly activates the complement system.
Nienke Oskam, Timon Damelang, Timon Damelang, Timon Damelang, Marij Streutker, Pleuni Ooijevaar-de Heer, Jan Nouta, Carolien Koeleman, Julie Van Coillie, Julie Van Coillie, Manfred Wuhrer, Gestur Vidarsson, Gestur Vidarsson, Theo Rispens   +13 more
doaj   +1 more source

Quantitative detection of red blood cell antibody-mediated complement activation

Zhongguo shuxue zazhi, 2022
Objective To construct an in-vitro model of erythrocyte antibody-mediated complement activation, and establish quantitative detection methods based on flow cytometry and spectrophotometry, so as to explore the correlation of anti-body titers and ...
Zhongying WANG, Jian LI, Fengyong ZHAO, Chenrui QIAN, Wei SHEN, Liangfeng FAN, Sha JIN, Jiewei ZHENG, Yuyu ZHANG, Dong XIANG   +9 more
doaj   +1 more source

Optimal transport and control of active drops [PDF]

PNAS 119 (35) e2121985119, 2022, 2021
Understanding the complex patterns in space-time exhibited by active systems has been the subject of much interest in recent times. Complementing this forward problem is the inverse problem of controlling active matter. Here we use optimal control theory to pose the problem of transporting a slender drop of an active fluid and determine the dynamical ...
arxiv   +1 more source

Molecular detection and antimicrobial activity of Endophytic fungi isolated from a medical plant Rosmarinus officinalis [PDF]

Vol 23, 2020, 14, 2023
Endophytes are tiny organisms present in living tissues of distinct plants and have been extensively studied for their endophytic microbial complement. Roots of Rosmarinus officinalis were subjected to the isolation of endophytic fungi and screened for antimicrobial activity against Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram ...
arxiv   +1 more source

Polyphosphates and Complement Activation

Frontiers in Medicine, 2019
To sustain life in environments that are fraught with risks of life-threatening injury, organisms have developed innate protective strategies such that the response to wounds is rapid and localized, with the simultaneous recruitment of molecular ...
Edward M. Conway
doaj   +1 more source