Results 31 to 40 of about 729,206 (315)
C1q as a target molecule to treat human disease: What do mouse studies teach us?
Frontiers in Immunology, 2022 The complement system is a field of growing interest for pharmacological intervention. Complement protein C1q, the pattern recognition molecule at the start of the classical pathway of the complement cascade, is a versatile molecule with additional non ...
Kristina Schulz +3 more
doaj +1 more source
C1q and phagocytosis: the perfect complement to a good meal [PDF]
Journal of Leukocyte Biology, 2012 Abstract Review on the role for C1q in enhancement of phagocytosis, specifically focusing on C1q-mediated clearance of apoptotic cells. Complement component C1q is a member of a family of soluble proteins called defense collagens, which are important in host defense and apoptotic cell clearance.
Manuel Galvan +2 more
openalex +5 more sources
Foods, 2023 The complement pathway is a major component of the innate immune system, which is critical for recognizing and clearing pathogens that rapidly react to defend the body against external pathogens.
Yihang Xing +8 more
doaj +1 more source
Echinococcus multilocularis Calreticulin Interferes with C1q-Mediated Complement Activation
Tropical Medicine and Infectious Disease, 2023 As a zoonotic disease caused by Echinococcus multilocularis larvae, alveolar echinococcosis (AE) is one of the most severe forms of parasitic infection. Over a long evolutional process E.
Siqi Xian +8 more
doaj +1 more source
RNAlater facilitates remote sampling of aquaculture Atlantic salmon liver for proteomic analysis
Aquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 578-586, December 2022., 2022 Graphical Abstract Proteomes of similar sizes were obtained in samples preserved by snap‐freezing or RNAlater. Proteins involved in transcriptional and translational machinery were affected in RNAlater stored samples. Abundance of published markers for heat and oxidative stress was not affected by snap‐freezing or RNAlater.
Anca G. Rusu +6 more
wiley +1 more source
Structure and evolution of neuronal wiring receptors and ligands
Developmental Dynamics, Volume 252, Issue 1, Page 27-60, January 2023., 2023 Abstract One of the fundamental properties of a neuronal circuit is the map of its connections. The cellular and developmental processes that allow for the growth of axons and dendrites, selection of synaptic targets, and formation of functional synapses use neuronal surface receptors and their interactions with other surface receptors, secreted ...
Elena Cortés +2 more
wiley +1 more source
Complementation of Subquandles [PDF]
Involve 18 (2025) 417-435, 2023 Saki and Kiani proved that the subrack lattice of a rack $R$ is necessarily complemented if $R$ is finite but not necessarily complemented if $R$ is infinite. In this paper, we investigate further avenues related to the complementation of subquandles.
arxiv +1 more source
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica +6 more
wiley +1 more source
Transcriptional factor PU.1 regulates decidual C1q expression in early pregnancy in human [PDF]
, 2015 "Copyright: © 2015 Madhukaran, Kishore, Jamil, Teo, Choolani and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Choolani, M +5 more
core +5 more sources
Cancer Research, 2020 Clinically-relevant radiotherapy induces aberrant complement activation, leading to brain injury. Microglia-selective genetic deletion of CNS complement C1q ameliorates radiation-induced cognitive impairments, synaptic loss, and neuroinflammation ...
Mineh Markarian +9 more
semanticscholar +1 more source