Results 11 to 20 of about 74,672 (291)
Frontiers in Genetics, 2021 Schizophrenia is a common neuropsychiatric disorder with complex pathophysiology. Recent reports suggested that complement system alterations contributed to pathological synapse elimination that was associated with psychiatric symptoms in schizophrenia ...
Yu Chen +11 more
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Arthritis Research & Therapy, 2021 Background Screening abnormal pathways and complement components in the kidneys of patients with lupus nephritis (LN) and NZB/W mice may help to identify complement-related therapeutic targets for LN.
Tao Liu +6 more
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Diverse Clinical Presentations of C3 Dominant Glomerulonephritis
Frontiers in Medicine, 2020 C3 dominant immunofluorescence staining is present in a subset of patients with idiopathic immune complex membranoproliferative glomerulonephritis (iMPGN).
Ramy M. Hanna +13 more
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Therapeutic Advances in Chronic Disease, 2020 Objective: To analyze the relationship between complement component 3 (C3) and the prevalence of cardiometabolic risk factors and disease activity in the rheumatic diseases having the highest rates of cardiovascular morbidity and mortality: rheumatoid ...
Iván Arias de la Rosa +17 more
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Analysis of C3 suggests three periods of positive selection events and different evolutionary patterns between fish and mammals. [PDF]
PLoS ONE, 2012 BACKGROUND: The third complement component (C3) is a central protein of the complement system conserved from fish to mammals. It also showed distinct characteristics in different animal groups.
Fanxing Meng +5 more
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Complement C3 deficiency alleviates alkylation-induced retinal degeneration in mice
Eye and Vision, 2022 Background It has been found that the extensive use of anticancer drugs containing DNA-alkylating agents not only target cancer cells but also cause retinal inflammation through toxic intermediates.
Lu Du, Guang-Hua Peng
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Circulating Complement Levels and C3 Glomerulopathy [PDF]
Clinical Journal of the American Society of Nephrology, 2014 The complement system is an essential part of innate immunity acting as a first-line defense against infection and provides an interface between innate and adaptive immunity ([1][1],[2][2]). It consists of a network of soluble (fluid phase) and cell membrane proteins (solid phase).
Sanjeev Sethi, Fernando C. Fervenza
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Recurrent pyogenic infections caused by a novel Gln1420* mutation in the C3 gene
Frontiers in Pediatrics, 2022 C3 is a crucial protein of the complement system. Congenital C3 deficiency is extremely rare and manifests through recurrent, severe infections and should always be considered as a differential diagnosis of recurrent pyogenic infections. We report a case
Pedro Simão Coelho +8 more
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Linchuang shenzangbing zazhi, 2021 Objective To explore the correlation between serum level of complement C3 and abdominal aortic calcification（AAC）in maintenance hemodialysis（MHD）patients.Methods A total of 127 MHD patients hospitalized between February 2019 and December 2019 were ...
Zhao Xin, Bi Chun-sheng
doaj
Linking Complement C3 and B Cells in Nasal Polyposis
Journal of Immunology Research, 2020 Nasal polyposis often is characterized by a persistent inflammation of the sinonasal mucosa, disease recurrence after medical or surgical intervention, and asthma comorbidity.
Ulrike Werner +7 more
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