Results 31 to 40 of about 862,879 (325)
Recurrent pyogenic infections caused by a novel Gln1420* mutation in the C3 gene
Frontiers in Pediatrics, 2022 C3 is a crucial protein of the complement system. Congenital C3 deficiency is extremely rare and manifests through recurrent, severe infections and should always be considered as a differential diagnosis of recurrent pyogenic infections. We report a case
Pedro Simão Coelho +8 more
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Linchuang shenzangbing zazhi, 2021 Objective To explore the correlation between serum level of complement C3 and abdominal aortic calcification（AAC）in maintenance hemodialysis（MHD）patients.Methods A total of 127 MHD patients hospitalized between February 2019 and December 2019 were ...
Zhao Xin, Bi Chun-sheng
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Linking Complement C3 and B Cells in Nasal Polyposis
Journal of Immunology Research, 2020 Nasal polyposis often is characterized by a persistent inflammation of the sinonasal mucosa, disease recurrence after medical or surgical intervention, and asthma comorbidity.
Ulrike Werner +7 more
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Conformational Complexity of Complement Component C3
, 2007 The structures of native C3 and its major fragment C3c have provided a wealth of structural insights into the central protein of the complement system. The proteolytic activation steps, generating the important fragments C3b and iC3b, are thought to induce significant conformational changes in the molecule, yielding protein molecules with distinct ...
Janssen, B.J.C., Gros, P.
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Frontiers in Immunology, 2021 The zoonotic intracellular bacterium Chlamydia psittaci causes life-threatening pneumonia in humans. During mouse lung infection, complement factor C3 and the anaphylatoxin C3a augment protection against C. psittaci by a so far unknown mechanism.
Martin Kohn +5 more
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Role of complement C3 in diabetic nephropathy
Linchuang shenzangbing zazhi, 2022 As one of the most common microvascular complications of diabetes， diabetic kidney disease （DKD） is one of the major causes of end-stage renal disease. Complement system participates in both innate and adaptive immunities of human body. Three pathways of
Wang Qing-qing +3 more
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Association of the porcine
Genetics Selection Evolution, 2003 The complement component C3 plays an essential role in the activated complement system, which is involved in phagocytosis, inflammation and immunoregulation to destroy infectious microorganisms.
Mekchay Supamit +3 more
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Assessment of the Role of C3(H2O) in the Alternative Pathway
Frontiers in Immunology, 2020 In this study we investigate the hydrolysis of C3 to C3(H2O) and its ability to initiate activation via the alternative pathway (AP) of the complement system.
Karin Fromell +9 more
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Complement content in plasma under different storage conditions
Zhongguo shuxue zazhi, 2023 Objective To investigate the changes in complement content in component blood before blood transfusion. Methods 180 samples from 20 plasma donors were collected at different stages of the preparation process, stored at different temperatures and time ...
Zhi HAN, Yujie HAN, Haihong ZHANG
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Defining the Complement Biomarker Profile of C3 Glomerulopathy [PDF]
Clinical Journal of the American Society of Nephrology, 2014 C3 glomerulopathy (C3G) applies to a group of renal diseases defined by a specific renal biopsy finding: a dominant pattern of C3 fragment deposition on immunofluorescence. The primary pathogenic mechanism involves abnormal control of the alternative complement pathway, although a full description of the disease spectrum remains to be determined.
Zhang, Yuzhou +8 more
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