Results 31 to 40 of about 268,987 (334)
Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
, 2016 Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
core +1 more source
Recurrent pyogenic infections caused by a novel Gln1420* mutation in the C3 gene
Frontiers in Pediatrics, 2022 C3 is a crucial protein of the complement system. Congenital C3 deficiency is extremely rare and manifests through recurrent, severe infections and should always be considered as a differential diagnosis of recurrent pyogenic infections. We report a case
Pedro Simão Coelho +8 more
doaj +1 more source
Differential Surface Deposition of Complement Proteins on Logarithmic and Stationary Phase Leishmania Chagasi Promastigotes [PDF]
, 2012 Previous works demonstrated that various species of Leishmania promastigotes exhibit differential sensitivity to complement-mediated lysis (CML) during development.
Beetham, Jeffrey +4 more
core +3 more sources
Frontiers in Immunology, 2021 The zoonotic intracellular bacterium Chlamydia psittaci causes life-threatening pneumonia in humans. During mouse lung infection, complement factor C3 and the anaphylatoxin C3a augment protection against C. psittaci by a so far unknown mechanism.
Martin Kohn +5 more
doaj +1 more source
Role of complement C3 in diabetic nephropathy
Linchuang shenzangbing zazhi, 2022 As one of the most common microvascular complications of diabetes， diabetic kidney disease （DKD） is one of the major causes of end-stage renal disease. Complement system participates in both innate and adaptive immunities of human body. Three pathways of
Wang Qing-qing +3 more
doaj
Association of the porcine
Genetics Selection Evolution, 2003 The complement component C3 plays an essential role in the activated complement system, which is involved in phagocytosis, inflammation and immunoregulation to destroy infectious microorganisms.
Mekchay Supamit +3 more
doaj +1 more source
Assessment of the Role of C3(H2O) in the Alternative Pathway
Frontiers in Immunology, 2020 In this study we investigate the hydrolysis of C3 to C3(H2O) and its ability to initiate activation via the alternative pathway (AP) of the complement system.
Karin Fromell +9 more
doaj +1 more source
Conformational Complexity of Complement Component C3
, 2007 The structures of native C3 and its major fragment C3c have provided a wealth of structural insights into the central protein of the complement system. The proteolytic activation steps, generating the important fragments C3b and iC3b, are thought to induce significant conformational changes in the molecule, yielding protein molecules with distinct ...
Janssen, B.J.C., Gros, P.
openaire +7 more sources
Complement content in plasma under different storage conditions
Zhongguo shuxue zazhi, 2023 Objective To investigate the changes in complement content in component blood before blood transfusion. Methods 180 samples from 20 plasma donors were collected at different stages of the preparation process, stored at different temperatures and time ...
Zhi HAN, Yujie HAN, Haihong ZHANG
doaj +1 more source
Терапевтический архив, 2023 Aim. To compare changes in the complement system in C3-glomerulopathy (C3-GP) and atypical hemolytic uremic syndrome (aHUS) after the relief of an acute episode of thrombotic microangiopathy. Materials and methods.
Valeriya A. Yurova +5 more
doaj +1 more source