Results 91 to 100 of about 27,207 (241)
Understanding how prey species tradeoff predation risk and resource acquisition is particularly important for advancing our knowledge of predator–prey relationships. We investigated this by studying the use of concentrated anthropogenic resources, namely supplementary feeding sites, by roe deer Capreolus capreolus before and after grey wolf Canis lupus
Federico Ossi +7 more
wiley +1 more source
The interaction between circulating complement proteins and cutaneous microvascular endothelial cells in the development of childhood Henoch-Schönlein Purpura. [PDF]
In addition to IgA, the deposition of complement (C)3 in dermal vessels is commonly found in Henoch-Schönlein purpura (HSP). The aim of this study is to elucidate the role of circulating complement proteins in the pathogenesis of childhood HSP.Plasma ...
Yao-Hsu Yang +5 more
doaj +1 more source
The tumour microenvironment links complement system dysregulation and hypoxic signalling. [PDF]
The complement system is an innate immune pathway typically thought of as part of the first line of defence against "non-self" species. In the context of cancer, complement has been described to have an active role in facilitating cancer-associated ...
Giaccia, Amato J +4 more
core +1 more source
Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong +217 more
wiley +1 more source
Innate immunity and neuroinflammation [PDF]
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core +3 more sources
In a randomized cross‐over trial, regional citrate anticoagulation provided superior biocompatibility over full‐dose unfractionated heparin during expanded hemodialysis with significantly lower activation of complement, granulocytes, and platelets without affecting dialysis efficiency. ABSTRACT Background Regional citrate anticoagulation (RCA) improves
Marija Malgaj Vrečko +7 more
wiley +1 more source
Complement C3a and C5a Induce Different Signal Transduction Cascades in Endothelial Cells [PDF]
Abstract In leukocytes, C3a and C5a cause chemotaxis in a Gi-dependent, pertussis toxin (PT)-sensitive fashion. Because we found that HUVECs and immortalized human dermal microvascular endothelial cells express small numbers of C3aRs and C5aRs, we asked what the function of these receptors was on these cells.
Ingrid U, Schraufstatter +4 more
openaire +2 more sources
Erythropoietin Effect on Complement Activation in Chronic Kidney Disease
The complement system is an important part of innate immunity. Despite its known protective role, the complement system may contribute to increased inflammation and tissue injury in cases where its balanced activation is disrupted.
Virginia Athanasiadou +8 more
doaj +1 more source
Complement 3a Mediates CCN2/CTGF in Human Retinal Pigment Epithelial Cells
Background. Complement 3 (C3) is the crucial component of the complement cascade when retina was exposed to external stimulus. Cellular communication network 2/connective tissue growth factor (CCN2/CTGF) is important in response of retinal stress and a ...
Kang Xiao +4 more
doaj +1 more source
Go Green or Go Digital? A Set‐Theoretic Perspective of Incumbents' Paths to Success
ABSTRACT In response to growing pressures for environmental sustainability and technological advancement, this study examines how firms can effectively integrate green and digital innovations within ambidextrous strategies to enhance performance. Using fuzzy‐set Qualitative Comparative Analysis (fsQCA) on a sample of 175 German manufacturing and ...
Bettina Mayr
wiley +1 more source

