Results 91 to 100 of about 49,845 (259)
Complement dysregulation in human tauopathies
Brain Pathology, EarlyView.Complement protein and activation product levels were assessed in post‐mortem frontal cortex from three distinct subtypes of Tauopathy: Corticobasal degeneration, globular glial tauopathy, and Pick's disease. Quantification of complement proteins by immunohistochemistry and ELISA showed elevation of key complement proteins (C1q) regulators (FI) and ...
Jacqui Nimmo +3 more
wiley +1 more source
C3A: A Cognitive Collaborative Control Architecture For an Intelligent Wheelchair [PDF]
arXiv, 2017 Retention of residual skills for persons who partially lose their cognitive or physical ability is of utmost importance. Research is focused on developing systems that provide need-based assistance for retention of such residual skills. This paper describes a novel cognitive collaborative control architecture C3A, designed to address the challenges of ...
arxiv
The Economic History Review, EarlyView.Abstract This study advances a new approach to investigating the resilience of regional banking systems by reconstructing the co‐evolving branch and interbank networks in post‐Confederation Canada (1879–1900). By digitizing annual banking registers, this study employed a microgeographic approach to constructing a novel longitudinal dataset on city ...
Alena V. Pivavarava
wiley +1 more source
Determination of Anaphylatoxin Concentrations in Suction Blisters in Patients with Psoriasis [PDF]
, 1986 Concentrations of C3a and C4a anaphylatoxins in suction blister fluids were determined by radioimmunoassay in patients with psoriasis and normal controls.
Ohkohchi, Kyoto +2 more
core +1 more source
Erythropoietin Effect on Complement Activation in Chronic Kidney Disease
BiomedicinesThe complement system is an important part of innate immunity. Despite its known protective role, the complement system may contribute to increased inflammation and tissue injury in cases where its balanced activation is disrupted.
Virginia Athanasiadou +8 more
doaj +1 more source
Protective immune response against Rhodococcus equi: An innate immunity‐focused review
Equine Veterinary Journal, Volume 57, Issue 3, Page 563-586, May 2025.Abstract Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune
Bibiana Petri da Silveira +4 more
wiley +1 more source
Ophthalmology Science, 2022 Purpose: To investigate the association of risk alleles in complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2) with complement activation products in the aqueous humor in eyes with neovascular age-related macular degeneration ...
Yutaka Kato, MD +11 more
doaj
Complement 3a Mediates CCN2/CTGF in Human Retinal Pigment Epithelial Cells
Journal of Ophthalmology, 2022 Background. Complement 3 (C3) is the crucial component of the complement cascade when retina was exposed to external stimulus. Cellular communication network 2/connective tissue growth factor (CCN2/CTGF) is important in response of retinal stress and a ...
Kang Xiao +4 more
doaj +1 more source
Decidability of Existence and Construction of a Complement of a given Function [PDF]
arXiv, 2011 This article defines a complement of a function and conditions for existence of such a complement function and presents few algorithms to construct a complement.
arxiv
Immunology, EarlyView.The membrane attack complex (MAC) is formed by the stepwise assembly of five proteins: C5b, C6, C7, C8 and C9. MAC plays a key role in driving inflammation in numerous diseases. This study compares the inhibitory mechanisms of MAC assembly by soluble CD59 (sCD59), a disulphide‐locked C9 mutant (C9lock) and horse C9 (HoC9).
Rebekah S. Cooke +5 more
wiley +1 more source