Results 101 to 110 of about 49,845 (259)
Nature Communications, 2017 Complement C3a is an important protein in innate and adaptive immunity, but its roles in vivo are unclear. Here the authors develop novel chemical agonists and antagonists for the C3a receptor, and show that they modulate mast cell degranulation and ...
Rink-Jan Lohman +13 more
doaj +1 more source
Complemented subspaces of products of Banach spaces [PDF]
arXiv, 2000 We show that complemented subspaces of uncountable products of Banach spaces are products of complemented subspaces of countable subproducts.
arxiv
Clinical Pharmacology &Therapeutics, Volume 118, Issue 1, Page 242-251, July 2025.Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost +9 more
wiley +1 more source
Enzymatic Reactions and Detection of C3 Cleavage Fragments
Bio-Protocol, 2014 The complement component C3 is the major effector molecule of the complement system. C3 circulates in the blood and interstitial fluids as pro-enzyme and is activated by enzymatic cleavage into a C3a portion, a classic anaphylatoxin that functions as ...
Claudia Kemper, Martin Kolev
doaj +1 more source
On the complemented subspaces of X_p [PDF]
arXiv, 1990 In this paper we prove some results related to the problem of isomorphically classifying the complemented subspaces of $X_{p}$. We characterize the complemented subspaces of $X_{p}$ which are isomorphic to $X_{p}$ by showing that such a space must contain a canonical complemented subspace isomorphic to $X_{p}.$ We also give some characterizations of ...
arxiv
Complement C3a Regulates Late Asthmatic Response and Airway Hyperresponsiveness in Mice [PDF]
The Journal of Immunology, 2009 Abstract Allergic asthma is a chronic inflammatory disorder of the airways characterized by biphasic airway obstruction and airway hyperresponsiveness. In this study, we attempted to elucidate the contribution of the complement C3a to these asthmatic symptoms. BALB/c mice sensitized by i.p.
Nobuaki Mizutani +2 more
openaire +3 more sources
Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets
MedComm, Volume 6, Issue 7, July 2025.This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song +9 more
wiley +1 more source
Лечащий ВрачBackground. Neuroinfections are one of the global medical and social problems of pediatrics, due to the high incidence of neurological complications that affect the further development of the child.Objective. To establish the clinical significance of the
G. A. Kharchenko, O. G. Kimirilova
doaj +1 more source
Classifying complements for conformal algebras [PDF]
arXiv, 2020 Let $R\subseteq E$ be two Lie conformal algebras and $Q$ be a given complement of $R$ in $E$. Classifying complements problem asks for describing and classifying all complements of $R$ in $E$ up to an isomorphism. It is known that $E$ is isomorphic to a bicrossed product of $R$ and $Q$.
arxiv
Engineering Reports, Volume 7, Issue 6, June 2025.Incorporating waste glass powder (GP) into cementitious mortars significantly reduces environmental impact, with a 35% decrease in embodied carbon and energy at 40% GP replacement. This study shows that GP enhances long‐term mechanical strength, cuts autoclave expansion by 50%, and refines microstructure through denser C‐S‐H formation.
Mahdi Bameri +4 more
wiley +1 more source