Results 91 to 100 of about 26,149 (232)

Complement activation by the artificial surface of cardiopulmonary bypass is a persistent clinical problem

Scientific Reports
Activation of the alternative complement pathway by artificial extracorporeal surfaces is relevant to several clinical applications such as cardiac surgery with cardiopulmonary bypass (CPB), thoracic organ transplantation and hemodialysis.
Joel David Bierer, Roger Stanzel, Mark Henderson, Tony El-Rabahi, John Sapp, Pantelis Andreou, Jean S. Marshall, David Conrad, David Horne   +8 more
doaj   +1 more source

The wolf is back! Non‐consumptive effects of the return of a large carnivore on the use of supplementary feeding sites by roe deer

Wildlife Biology, EarlyView.
Understanding how prey species tradeoff predation risk and resource acquisition is particularly important for advancing our knowledge of predator–prey relationships. We investigated this by studying the use of concentrated anthropogenic resources, namely supplementary feeding sites, by roe deer Capreolus capreolus before and after grey wolf Canis lupus
Federico Ossi, Moniek Heurman, Arnaud Bruat, Charlotte Vanderlocht, Benjamin Robira, Nathan Ranc, Simone Dal Farra, Francesca Cagnacci   +7 more
wiley   +1 more source

Enzymatic Reactions and Detection of C3 Cleavage Fragments

Bio-Protocol, 2014
The complement component C3 is the major effector molecule of the complement system. C3 circulates in the blood and interstitial fluids as pro-enzyme and is activated by enzymatic cleavage into a C3a portion, a classic anaphylatoxin that functions as ...
Claudia Kemper, Martin Kolev
doaj   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

Generalizing Negative Imaginary Systems Theory to Include Free Body Dynamics: Control of Highly Resonant Structures with Free Body Motion [PDF]

, 2013
Negative imaginary (NI) systems play an important role in the robust control of highly resonant flexible structures. In this paper, a generalized NI system framework is presented.
Kallapur, A. G., Lanzon, A., Mabrok, M. A., Petersen, I. R.   +3 more
core   +1 more source

The Complement C3a And C3a Receptor Pathway Indiabetic Patients With Entamobra Histolytica, Cryptospridium Parvum

International Journal of Environmental Sciences
Cryptosporidium parvum and Entamoeba histolytica are significant protozoan parasites that adversely impact human health. The infection rate of these parasites among diabetic patients was recorded at 18.33%. However, the mechanisms underlying host-parasite interactions remain poorly understood.
Bafreen Mohamad Raza, Naema Ali Ahmed, Sahlah Kh. Abbas   +2 more
openaire   +1 more source

Clinical significance of circulating immune complexes and components of the blood complement system in viral meningitis in children

Лечащий Врач
Background. Neuroinfections are one of the global medical and social problems of pediatrics, due to the high incidence of neurological complications that affect the further development of the child.Objective. To establish the clinical significance of the
G. A. Kharchenko, O. G. Kimirilova
doaj   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Comparison of Biocompatibility and Efficacy of Regional Citrate Anticoagulation and Unfractionated Heparin During Expanded Hemodialysis With a Medium Cut‐Off Membrane—A Randomized Trial

Artificial Organs, EarlyView.
In a randomized cross‐over trial, regional citrate anticoagulation provided superior biocompatibility over full‐dose unfractionated heparin during expanded hemodialysis with significantly lower activation of complement, granulocytes, and platelets without affecting dialysis efficiency. ABSTRACT Background Regional citrate anticoagulation (RCA) improves
Marija Malgaj Vrečko, Jernej Pajek, Jakob Gubenšek, Samo Hudoklin, Joško Osredkar, Mojca Božič Mijovski, Aleš Jerin, Jadranka Buturović‐Ponikvar   +7 more
wiley   +1 more source

Complement System Part II: Role in Immunity [PDF]

, 2015
International audienceThe complement system has been considered for a long time as a simple lytic cascade, aimed to kill bacteria infecting the host organism.
Fremeaux-Bacchi, Veronique, Halbwachs-Mecarelli, Lise, Merle, Nicolas S., Noe, Remi, Roumenina, Lubka T.   +4 more
core   +6 more sources