Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice [PDF]
Akk, Antonina +11 more
core +1 more source
Donor pretreatment with nebulized complement C3a receptor antagonist mitigates brain-death induced immunological injury post-lung transplant. [PDF]
Cheng Q +10 more
europepmc +1 more source
Complement C3a receptor antagonism for ME/CFS neuroinflammation
Complement component 3a receptor (C3AR1) is activated by elevated C3a levels in ME/CFS patients, triggering microglial activation and neuroinflammation in brain regions controlling fatigue and cognitive function. C3AR1 antagonists like SB290157 or PMX205 could reduce complement-mediated neuroinflammation and improve central nervous system symptoms.
openaire +1 more source
C/EBP-β-regulated complement hyperactivation in spleen of SFTSV-infected mice: A clue to targeted complement therapy. [PDF]
Liu Y +12 more
europepmc +1 more source
Targeting the C3 signaling axis of the complement system: immune microenvironment regulation and emerging therapeutic strategies for glioblastoma. [PDF]
Huang J, Wang Q, Chen J.
europepmc +1 more source
The Complement System in the Setting of Critical Illness-A Narrative Review. [PDF]
Ampelakiotou K +5 more
europepmc +1 more source
The Role of Complement Anaphylatoxins (C3a and C5a) in Non-small Cell Lung Cancer: A Systematic Review. [PDF]
Skarentzos K +4 more
europepmc +1 more source
Complement and inflammasome crosstalk in chronic inflammation. [PDF]
Janžič L, Kouter K.
europepmc +1 more source
Complement system in cancer: friend or foe of immunotherapy. [PDF]
Shah HK +6 more
europepmc +1 more source

