Results 51 to 60 of about 13,347 (154)
Cell Transplantation, 1998 Cells from primary porcine hepatocytes (PPH) and the immortalized human hepatoma cell line C3A are both used in bioartificial liver support systems (BALSS).
Lisheng Wang +5 more
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Preservation of Antimicrobial Properties of Complement Peptide C3a, from Invertebrates to Humans [PDF]
Journal of Biological Chemistry, 2007 The human anaphylatoxin peptide C3a, generated during complement activation, exerts antimicrobial effects. Phylogenetic analysis, sequence analyses, and structural modeling studies paired with antimicrobial assays of peptides from known C3a sequences showed that, in particular in vertebrate C3a, crucial structural determinants governing antimicrobial ...
Pasupuleti, Mukesh +5 more
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Complement 3a Mediates CCN2/CTGF in Human Retinal Pigment Epithelial Cells
Journal of Ophthalmology, 2022 Background. Complement 3 (C3) is the crucial component of the complement cascade when retina was exposed to external stimulus. Cellular communication network 2/connective tissue growth factor (CCN2/CTGF) is important in response of retinal stress and a ...
Kang Xiao +4 more
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Complement C3a and C5a Induce Different Signal Transduction Cascades in Endothelial Cells [PDF]
The Journal of Immunology, 2002 Abstract In leukocytes, C3a and C5a cause chemotaxis in a Gi-dependent, pertussis toxin (PT)-sensitive fashion. Because we found that HUVECs and immortalized human dermal microvascular endothelial cells express small numbers of C3aRs and C5aRs, we asked what the function of these receptors was on these cells.
Ingrid U, Schraufstatter +4 more
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Erythropoietin Effect on Complement Activation in Chronic Kidney Disease
BiomedicinesThe complement system is an important part of innate immunity. Despite its known protective role, the complement system may contribute to increased inflammation and tissue injury in cases where its balanced activation is disrupted.
Virginia Athanasiadou +8 more
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The interaction between circulating complement proteins and cutaneous microvascular endothelial cells in the development of childhood Henoch-Schönlein Purpura. [PDF]
PLoS ONE, 2015 In addition to IgA, the deposition of complement (C)3 in dermal vessels is commonly found in Henoch-Schönlein purpura (HSP). The aim of this study is to elucidate the role of circulating complement proteins in the pathogenesis of childhood HSP.Plasma ...
Yao-Hsu Yang +5 more
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International Journal of Environmental SciencesCryptosporidium parvum and Entamoeba histolytica are significant protozoan parasites that adversely impact human health. The infection rate of these parasites among diabetic patients was recorded at 18.33%. However, the mechanisms underlying host-parasite interactions remain poorly understood.
Bafreen Mohamad Raza +2 more
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Scientific ReportsActivation of the alternative complement pathway by artificial extracorporeal surfaces is relevant to several clinical applications such as cardiac surgery with cardiopulmonary bypass (CPB), thoracic organ transplantation and hemodialysis.
Joel David Bierer +8 more
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HeliyonIndoor exposure to microbial growth, caused by moisture damage, has been an established health risk for several decades. It is likely that a damp indoor environment contains biological pollutants that trigger both the innate and adaptive branches of the ...
Outi Karhuvaara +4 more
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Nature Communications, 2017 Complement C3a is an important protein in innate and adaptive immunity, but its roles in vivo are unclear. Here the authors develop novel chemical agonists and antagonists for the C3a receptor, and show that they modulate mast cell degranulation and ...
Rink-Jan Lohman +13 more
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