Results 51 to 60 of about 49,845 (259)
Complement peptide receptors in GtoPdb v.2021.3 [PDF]
, 2021 Complement peptide receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Complement peptide receptors [107]) are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a and C5a, generated upon stimulation of the complement ...
Cianciulli, Antonia +8 more
core +2 more sources
A statistical-thermodynamic analysis of stably ordered substitutional structures in graphene [PDF]
Physica E, vol. 42, 2047-2054 (2010), 2014 Ordered distributions of carbon and substitutional dopant (A) atoms over the sites of a graphene lattice and problem of their stability are considered theoretically. The ranges of values of interatomic-interaction parameters providing the low-temperature stability of the graphene-based C7A, C3A, and CA superstructures are determined within the ...
arxiv +1 more source
Complement activation and its prognostic role in post-cardiac arrest patients [PDF]
, 2014 Cardiac arrest causes generalized ischemia/hypoxia, and subsequent resuscitation inflicts reperfusion injury, the pathology of which is not fully understood.
Bisschops +17 more
core +1 more source
Astrocyte Responses to Complement Peptide C3a are Highly Context-Dependent
Neurochemical Research, 2022 AbstractAstrocytes perform a range of homeostatic and regulatory tasks that are critical for normal functioning of the central nervous system. In response to an injury or disease, astrocytes undergo a pronounced transformation into a reactive state that involves changes in the expression of many genes and dramatically changes astrocyte morphology and ...
Pekna, Marcela +5 more
openaire +2 more sources
Journal of Innate Immunity, 2021 To study the molecular interplay between TLRs and complement representing ancient danger-sensing mechanisms, we examined the regulation of the C3a/anaphylatoxin C3a receptor (C3aR) axis in normal human epidermal keratinocytes (NHEKs) by treatment with ...
Susanne Mommert +5 more
doaj +1 more source
An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA. [PDF]
, 2015 Antibody-mediated rejection (AMR) of solid organ transplants (SOT) is characterized by damage triggered by donor-specific antibodies (DSA) binding donor Class I and II HLA (HLA-I and HLA-II) expressed on endothelial cells.
Fishbein, MC +7 more
core +1 more source
Biomedicines, 2023 The liver has a huge impact on the functioning of our body and the preservation of homeostasis. It is exposed to many serious diseases, which may lead to the chronic failure of this organ, which is becoming a global health problem today.
Marta Budkowska +11 more
doaj +1 more source
Commensurability classes of 2-bridge knot complements [PDF]
Algebr. Geom. Topol. 8 (2008) 1031-1057, 2006 We show that a hyperbolic 2-bridge knot complement is the unique knot complement in its commensurability class. We also discuss constructions of commensurable hyperbolic knot complements and put forth a conjecture on the number of hyperbolic knot complements in a commensurability class.
arxiv +1 more source
Potential Mechanisms Underlying TGF-β-mediated Complement Activation in Lung Fibrosis [PDF]
, 2017 While our previous studies suggest that limiting bleomycin-induced complement activation suppresses TGF-β signaling, the specific hierarchical interactions between TGF-β and complement in lung fibrosis are unclear.
Cipolla, Ellyse +5 more
core +2 more sources
Cancer epithelia-derived mitochondrial DNA is a targetable initiator of a paracrine signaling loop that confers taxane resistance. [PDF]
, 2020 Stromal-epithelial interactions dictate cancer progression and therapeutic response. Prostate cancer (PCa) cells were identified to secrete greater concentration of mitochondrial DNA (mtDNA) compared to noncancer epithelia.
Agarwal, Priyanka +11 more
core