Results 71 to 80 of about 13,347 (154)

Association of age-related macular degeneration with complement activation products, smoking, and single nucleotide polymorphisms in South Carolinians of European and African descent

Molecular Vision, 2019
Purpose: Smoking and the incidence of age-related macular degeneration (AMD) have been linked to an overactive complement system. Here, we examined in a retrospective cohort study whether AMD-associated single nucleotide polymorphisms (SNPs), smoking ...
Bärbel Rohrer, Ashley Frazer-Abel, Anthony Leonard, Rinki Ratnapriya, Tyson Ward, Alexandra Pietraszkiewicz, Elizabeth O’Quinn, Katherine Adams, Anand Swaroop, Bethany Jacobs Wolf   +9 more
doaj  

Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity. [PDF]

J Clin Invest, 2023
Stokowska A, Aswendt M, Zucha D, Lohmann S, Wieters F, Morán Suarez J, Atkins AL, Li Y, Miteva M, Lewin J, Wiedermann D, Diedenhofen M, Torinsson Naluai Å, Abaffy P, Valihrach L, Kubista M, Hoehn M, Pekny M, Pekna M.   +18 more
europepmc   +1 more source

Functional mass spectrometry indicates anti-protease and complement activity increase with COVID-19 severity

Experimental Biology and Medicine
Investigations on some innate immunity proteins can yield misleading information, as investigators often rely on static measurements and assume a direct correlation to function. As protein function is often not directly proportional to protein abundance,
Douglas D. Fraser, Douglas D. Fraser, Swapan Roy, Matt Kuruc, Maritza Quintero, Logan R. Van Nynatten, Gediminas Cepinskas, Gediminas Cepinskas, Haiyan Zheng, Amenah Soherwardy, Devjit Roy   +10 more
doaj   +1 more source

The Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer. [PDF]

Cancer Res Commun, 2022
Sodji QH, Nambiar DK, Viswanathan V, von Eyben R, Colburg D, Binkley MS, Li CG, Olcina MM, Chang DT, Le QT, Giaccia AJ.   +10 more
europepmc   +1 more source

Complement C3a Measurement [PDF]

, 2020
openaire   +1 more source

Complement C3a receptor-mediated vascular dysfunction: a complex interplay between aging and neurodegeneration. [PDF]

J Clin Invest, 2021
Bhatia K, Ahmad S, Kindelin A, Ducruet AF.   +3 more
europepmc   +1 more source

The complement C3a-C3aR and C5a-C5aR pathways promote viability and inflammation of human retinal pigment epithelium cells by targeting NF-κB signaling. [PDF]

Exp Ther Med, 2022
Luo S, Xu H, Gong X, Shen J, Chen X, Wu Z.   +5 more
europepmc   +1 more source

Complement C3a activates osteoclasts by regulating the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma. [PDF]

Cancer Biol Med, 2021
Jiang F, Liu H, Peng F, Liu Z, Ding K, Song J, Li L, Chen J, Shao Q, Yan S, De Veirman K, Vanderkerken K, Fu R.   +12 more
europepmc   +1 more source

Hyperactive Behavior and Altered Brain Morphology in Adult Complement C3a Receptor Deficient Mice. [PDF]

Front Immunol, 2021
Pozo-Rodrigálvarez A, Ollaranta R, Skoog J, Pekny M, Pekna M.   +4 more
europepmc   +1 more source

The Complex Role of the Complement C3a Receptor (C3aR) in Cerebral Injury and Recovery Following Ischemic Stroke. [PDF]

Cells
Akhter N, Lambay A, Almotairi R, Hamadi A, Bhatia K, Ahmad S, Ducruet AF.   +6 more
europepmc   +1 more source