Results 81 to 90 of about 27,207 (241)

Alpine ungulates adjust diel activity to the natural return of wolves amid anthropogenic pressures

Ecography, EarlyView.
As wolves recolonise their historical range across Europe, ungulates face predation once more – but in landscapes profoundly altered by human activity. This shift raises crucial questions about their capacity to express adaptive antipredator behaviours.
Charlotte Vanderlocht, Valerio Donini, Andrea Corradini, Simone Dal Farra, Benjamin Robira, Andrea Gazzola, Giorgia Galeotti, Laura Limonciello, Noemi Squillaci, Maël Van Dam, Giada Zeni, Marta Gandolfi, Elisa Iacona, Lucrezia Lorenzetti, Matteo Nava, Federico Ossi, Heidi C. Hauffe, Francesco Ferretti, Luca Corlatti, Luca Pedrotti, Francesca Cagnacci   +20 more
wiley   +1 more source

Inhibition of Plasma Kallikrein with Aprotinin in porcine endotoxin Shock [PDF]

, 1993
Activation of the contact phase of coagulation has been implicated in the pathogenesis of septic shock. We wanted to determine if inhibition of plasma kallikrein can prevent arterial hypotension and liberation of kinins from kininogen, induced by an ...
Fink, Edwin, Fritz, Hans, Jochum, Marianne, Kroworsch, Peter, Schweiberer, Leonhard, Shimamoto, Kazuaki, Siebeck, Matthias, Spannagl, Michael, Weipert, Joachim   +8 more
core   +1 more source

Generalizing Negative Imaginary Systems Theory to Include Free Body Dynamics: Control of Highly Resonant Structures with Free Body Motion [PDF]

, 2013
Negative imaginary (NI) systems play an important role in the robust control of highly resonant flexible structures. In this paper, a generalized NI system framework is presented.
Kallapur, A. G., Lanzon, A., Mabrok, M. A., Petersen, I. R.   +3 more
core   +1 more source

Definition of a sensory lexicon and development of sensory wheels of eighteen monovarietal Italian white wines

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Italy harbors one of the richest grapevine biodiversities worldwide, yet the sensory identity of wines from many native cultivars remains poorly defined despite their relevance on the market at regional, national, or international levels.
Paola Piombino, Elisabetta Pittari, Roberto Salvatore Di Fede, Maria Tiziana Lisanti, Silvia Carlin, Andrea Curioni, Giovanni Luzzini, Christine Mayr Marangon, Matteo Marangon, Fulvio Mattivi, Maria Alessandra Paissoni, Giuseppina Paola Parpinello, Maurizio Piergiovanni, Arianna Ricci, Susana Río Segade, Luca Rolle, Maurizio Ugliano, Luigi Moio   +17 more
wiley   +1 more source

Complement Fragment C3a Controls Mutual Cell Attraction during Collective Cell Migration [PDF]

Developmental Cell, 2011
Collective cell migration is a mode of movement crucial for morphogenesis and cancer metastasis. However, little is known about how migratory cells coordinate collectively. Here we show that mutual cell-cell attraction (named here coattraction) is required to maintain cohesive clusters of migrating mesenchymal cells. Coattraction can counterbalance the
Carmona-Fontaine, Carlos, Theveneau, Eric, Tzekou, Apostolia, Tada, Masazumi, Woods, Mae, Page, Karen M., Parsons, Madeline, Lambris, John D., Mayor, Roberto   +8 more
openaire   +3 more sources

Denaturation and unfolding of human anaphylatoxin C3a: an unusually low covalent stability of its native disulfide bonds. [PDF]

, 2008
The complement C3a anaphylatoxin is a major molecular mediator of innate immunity. It is a potent activator of mast cells, basophils and eosinophils and causes smooth muscle contraction.
Chang, Jui-Yoa, Lin, Curtis C-J, Pangburn, Michael K, Salamanca, Silvia, Wetsel, Rick A   +4 more
core   +1 more source

Reprogramming Immunogenicity of Iron Oxide Nanoparticles through Sulfated Glycan Presentation

Small, EarlyView.
This study presents a comparative analysis of heparin (HP)‐ and dextran sulfate (DS)‐coated superparamagnetic iron oxide nanoparticles (SPIONs) as a tunable immunomodulatory platform where surface chemistry dictates therapeutic function. DS‐SPIONs are preferentially internalized by myeloid cells, reprogramming them into a pro‐healing M2 phenotype ...
Negin Pournoori, Heela Sarlus, Dick J. Sjöström, Rohith Pavan Parvathaneni, Oommen P. Varghese, Vesa P. Hytönen, Robert A. Harris, Per H. Nilsson, Oommen P. Oommen   +8 more
wiley   +1 more source

Preservation of Antimicrobial Properties of Complement Peptide C3a, from Invertebrates to Humans [PDF]

Journal of Biological Chemistry, 2007
The human anaphylatoxin peptide C3a, generated during complement activation, exerts antimicrobial effects. Phylogenetic analysis, sequence analyses, and structural modeling studies paired with antimicrobial assays of peptides from known C3a sequences showed that, in particular in vertebrate C3a, crucial structural determinants governing antimicrobial ...
Pasupuleti, Mukesh, Walse, Bjorn, Nordahl, Emma, Mörgelin, Matthias, Malmsten, Martin, Schmidtchen, Artur   +5 more
openaire   +4 more sources

Comparison of Porcine Hepatocytes with Human Hepatoma (C3A) Cells for Use in a Bioartificial Liver Support System

Cell Transplantation, 1998
Cells from primary porcine hepatocytes (PPH) and the immortalized human hepatoma cell line C3A are both used in bioartificial liver support systems (BALSS).
Lisheng Wang, Junhong Sun, Li Li, Douglas Mears, Margret Horvat, AG Ross Sheil   +5 more
doaj   +1 more source

C1q-targeted inhibition of the classical complement pathway prevents injury in a novel mouse model of acute motor axonal neuropathy [PDF]

, 2016
Introduction Guillain-Barré syndrome (GBS) is an autoimmune disease that results in acute paralysis through inflammatory attack on peripheral nerves, and currently has limited, non-specific treatment options.
Barrie, Jennifer A., Cunningham, Madeleine E., Fewou, Simon N., Furukawa, Koichi, McGonigal, Rhona, Sankaranarayanan, Sethu, Willison, Hugh J., Yao, Denggao, Yednock, Ted A.   +8 more
core   +2 more sources