Results 31 to 40 of about 712,823 (260)
Frontiers in Immunology, 2022 Multidrug-resistant Acinetobacter baumannii is known to be one of the leading pathogens that cause severe nosocomial infections. To overcome eradication by the innate immune system during infection, A.
Julia I. Ries +6 more
doaj +1 more source
Increased frequency of the null allele at the complement C4b locus in autism [PDF]
Clinical and Experimental Immunology, 1991 SUMMARY Associations between C4 deficiency and autoimmune disorders have been found over the past several years. Since autism has several autoimmune features, the frequencies of null (no protein produced) alleles at the C4A and C4B loci were studied in 19 subjects with autism and their family members.
Reed P. Warren +6 more
semanticscholar +3 more sources
The C4A and C4B Isotypic Forms of Human Complement Fragment C4b Have the Same Intrinsic Affinity for Complement Receptor 1 (CR1/CD35) [PDF]
The Journal of Immunology, 2004 AbstractSeveral previous reports concluded that the C4b fragment of human C4A (C4Ab) binds with higher affinity to CR1 than does C4Bb. Because the isotypic residues, 1101PCPVLD and 1101LSPVIH in C4A and C4B, respectively, are located within the C4d region, one may have expected a direct binding contribution of C4d to the interaction with CR1.
Liliana, Clemenza, David E, Isenman
openaire +4 more sources
Research and Practice in Thrombosis and Haemostasis, 2022 Background The factor XIII (FXIII)‐B subunit has a critical function as a carrier protein to stabilize FXIII‐A in plasma and supply it to its main substrate, fibrinogen.
Bojun Li +4 more
doaj +1 more source
C4Bgene influences intestinal microbiota through complement activation in patients with paediatric-onset inflammatory bowel disease [PDF]
Clinical and Experimental Immunology, 2017 Eija Nissilä +8 more
openalex +2 more sources
Molecules, 2022 Exosomes are small extracellular vesicles with a variable protein cargo in consonance with cell origin and pathophysiological conditions. Gestational diabetes mellitus (GDM) is characterized by different levels of chronic low-grade inflammation and ...
Elena G. Bernea +9 more
doaj +1 more source
Journal of Immunology, 2020 Key Points hC4Nb8 is a potent cross-reactive inhibitor of CP and LP proconvertase formation. hC4Nb8 binds to a neoepitope exposed upon C4 activation and C4b generation. hC4Nb8 inhibits the CP of complement in vivo.
A. Zarantonello +12 more
semanticscholar +1 more source
Multiple activities of LigB potentiate virulence of Leptospira interrogans: inhibition of alternative and classical pathways of complement. [PDF]
PLoS ONE, 2012 Microbial pathogens acquire the immediate imperative to avoid or counteract the formidable defense of innate immunity as soon as they overcome the initial physical barriers of the host. Many have adopted the strategy of directly disrupting the complement
Henry A Choy
doaj +1 more source
The role of salivary and intestinal complement system inhibitors in the midgut protection of triatomines and mosquitoes. [PDF]
PLoS ONE, 2009 Saliva of haematophagous arthropods contain biomolecules involved directly or indirectly with the haematophagy process, and among them are encountered some complement system inhibitors.
Veruska Cavalcanti Barros +7 more
doaj +1 more source