Results 31 to 40 of about 697,969 (251)

Human genes for the alpha and beta chains of complement C4b-binding protein are closely linked in a head-to-tail arrangement. [PDF]

open access: bronzeProceedings of the National Academy of Sciences of the United States of America, 1990
F. Pardo-Manuel   +4 more
semanticscholar   +2 more sources

Significance of urine complement proteins in monitoring lupus activity [PDF]

open access: yesPeerJ, 2022
Objectives Complement activation is a critical feature in the development of systemic lupus erythematosus (SLE). Whether there are changes of complement components in the urine of SLE has not been reported.
Jin Zhao   +5 more
doaj   +2 more sources

A Novel Antitumor Strategy: Simultaneously Inhibiting Angiogenesis and Complement by Targeting VEGFA/PIGF and C3b/C4b [PDF]

open access: goldMolecular Therapy: Oncolytics, 2019
Huiling Wang   +17 more
semanticscholar   +2 more sources

Structure-Based Modeling of Complement C4 Mediated Neutralization of Adenovirus

open access: yesViruses, 2021
Adenovirus (AdV) infection elicits a strong immune response with the production of neutralizing antibodies and opsonization by complement and coagulation factors.
Corey C. Emerson, Phoebe L. Stewart
doaj   +1 more source

Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes

open access: yesFrontiers in Cellular Neuroscience, 2023
Complement system plays an important role in the immune defense against pathogens; however, recent studies demonstrated an important role of complement subunits C1q, C4, and C3 in normal functions of the central nervous system (CNS) such as non ...
Tatyana Veremeyko   +8 more
doaj   +1 more source

Synovial Complement Factors in Patients with Periprosthetic Joint Infection after Undergoing Revision Arthroplasty of the Hip or Knee Joint

open access: yesDiagnostics, 2021
The role and diagnostic value of the synovial complement system in patients with low-grade periprosthetic joint infection (PJI) are unclear. We sought to evaluate, for the first time, the usefulness of synovial complement factors in these patients by ...
Frank Sebastian Fröschen   +6 more
doaj   +1 more source

Acquisition of complement inhibitor serine protease factor I and its cofactors C4b-binding protein and factor H by Prevotella intermedia. [PDF]

open access: yesPLoS ONE, 2012
Infection with the Gram-negative pathogen Prevotella intermedia gives rise to periodontitis and a growing number of studies implies an association of P. intermedia with rheumatoid arthritis.
Sven Malm   +5 more
doaj   +1 more source

CipA mediates complement resistance of Acinetobacter baumannii by formation of a factor I-dependent quadripartite assemblage

open access: yesFrontiers in Immunology, 2022
Multidrug-resistant Acinetobacter baumannii is known to be one of the leading pathogens that cause severe nosocomial infections. To overcome eradication by the innate immune system during infection, A.
Julia I. Ries   +6 more
doaj   +1 more source

Exploring the function of factor XIII free B subunit: Interactions with complement factors and a novel approach to identify potential binding partners

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2022
Background The factor XIII (FXIII)‐B subunit has a critical function as a carrier protein to stabilize FXIII‐A in plasma and supply it to its main substrate, fibrinogen.
Bojun Li   +4 more
doaj   +1 more source

Exosome Proteomics Reveals the Deregulation of Coagulation, Complement and Lipid Metabolism Proteins in Gestational Diabetes Mellitus

open access: yesMolecules, 2022
Exosomes are small extracellular vesicles with a variable protein cargo in consonance with cell origin and pathophysiological conditions. Gestational diabetes mellitus (GDM) is characterized by different levels of chronic low-grade inflammation and ...
Elena G. Bernea   +9 more
doaj   +1 more source

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