Results 111 to 120 of about 38,195 (255)

Phenotype- and age-associated variations in non-specific agglutinins and complement components (C3 and C5a) in camels: Implications for transfusion compatibility and immune function [PDF]

Veterinary World
Background and Aim: Blood transfusion in camels is hindered by poorly understood blood group systems, non-specific agglutinins, and a lack of standardized cross-matching protocols.
Yousef M. Alharbi
doaj   +1 more source

Innate immunity and neuroinflammation [PDF]

, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core   +3 more sources

Cancer‐Specific Antihuman Podoplanin Antibody chLpMab‐2f Exerts Antitumor Effects Against Pleural Mesothelioma

Cancer Science, EarlyView.
Cancer‐specific antihuman podoplanin antibody chLpMab‐2f exerted antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity against pleural mesothelioma (PM) cell lines. Additionally, chLpMab‐2f inhibited tumor progression in mice with subcutaneously and intrathoracically transplanted human PM cells.
Aito Yoshida, Shinji Abe, Toshihiro Izumi, Satoshi Itakura, Keichiro Yamada, Takuya Wada, Takaaki Yamamoto, Chiemi Sato, Atsushi Mitsuhashi, Hirokazu Ogino, Seidai Sato, Tsutomu Shinohara, Masaki Hanibuchi, Mika K. Kaneko, Yukinari Kato, Yasuhiko Nishioka   +15 more
wiley   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

New Hydrophilic Helixone Dialyzers as an Alternative for Hemodialysis Patients With Membrane Hypersensitivity Reactions: A Retrospective Single‐Cohort Study

Hemodialysis International, EarlyView.
ABSTRACT Background Synthetic dialysis membranes, particularly those composed of polysulfone blended with polyvinylpyrrolidone, are commonly used in hemodialysis due to their efficiency. However, hypersensitivity reactions—often atypical and not fitting traditional type A and B classifications—have increasingly been reported.
Víctor Joaquín Escudero‐Saiz, Elena Cuadrado‐Payán, Eugenia Castellote, Roxana Buri, Higini Cao, Silvia Collado, Lida Maria Rodas, Néstor Fontseré, José Jesús Broseta, Francisco Maduell   +9 more
wiley   +1 more source

The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients

Intensive Care Medicine Experimental, 2020
Background Mechanical ventilation can induce or even worsen lung injury, at least in part via overdistension caused by too large volumes or too high pressures.
Friso M. de Beer, Luuk Wieske, Gerard van Mierlo, Diana Wouters, Sacha Zeerleder, Lieuwe D. Bos, Nicole P. Juffermans, Marcus J. Schultz, Tom van der Poll, Wim K. Lagrand, Janneke Horn, for the BASIC–study group   +11 more
doaj   +1 more source

Porphyromonas gingivalis periodontal infection and its putative links with Alzheimer’s disease [PDF]

, 2015
Periodontal disease (PD) and Alzheimer’s disease (AD) are inflammatory conditions affecting the global adult population. In the pathogenesis of PD, subgingival complex bacterial biofilm induces inflammation that leads to connective tissue degradation and
Crean, Stjohn, Harding, Alice, Kesavalu, Lakshmyya, Poole, Sophie, Singhrao, Simarjit Kaur   +4 more
core   +3 more sources

First successful protocol for desensitization to eptinezumab

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Eptinezumab is an anti‐calcitonin gene‐related peptide monoclonal antibody used for migraine prevention. During clinical trials, hypersensitivity to eptinezumab was described without a clear underlying mechanism. To determine if the reaction was immunoglobulin E–mediated, the team of Nice University Hospital (Nice, France) performed
Benoit Gerard, Hubert Praudel, Michel Lanteri‐Minet, Elise Van Obberghen, Fanny Rocher‐Moreau, Johanna Rousset, Ulysse Jacquier, Sylvie Leroy, Margot Delin   +8 more
wiley   +1 more source

Complementing Cancer Metastasis

Frontiers in Immunology, 2018
Complement is an effector of innate immunity and a bridge connecting innate immunity and subsequent adaptive immune responses. It is essential for protection against infections and for orchestrating inflammatory responses.
Dawn M. Kochanek, Shanawaz M. Ghouse, Magdalena M. Karbowniczek, Maciej M. Markiewski   +3 more
doaj   +1 more source

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

Immunology, EarlyView.
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat, Priyanka Khatri, Youssif M. Ali, Chanuka H. Arachchilage, Gregory Demopulos, Kirsten Baillie, Kelly L. Miners, Kristin Ladell, Samantha A. Jones, Helen E. Davies, David A. Price, Wioleta M. Zelek, B. Paul Morgan, Wilhelm J. Schwaeble, Nicholas J. Lynch   +14 more
wiley   +1 more source