Valproic acid attenuates cellular senescence in diabetic kidney disease through the inhibition of complement C5a receptors. [PDF]
Sci Rep, 2022 Coughlan MT +4 more
europepmc +1 more source
Atherosclerotic Cardiovascular Disease and Cancer
Immunological Reviews, Volume 340, Issue 1, July 2026.ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) and cancer are increasingly recognized as interconnected diseases linked by shared immune mechanisms rather than merely overlapping risk factors. Common exposures such as smoking, obesity, diabetes, and dyslipidemia, together with aging and clonal hematopoiesis of indeterminate potential (CHIP ...
Anaïs Amend +4 more
wiley +1 more source
In Vivo Pharmacodynamic Method to Assess Complement C5a Receptor Antagonist Efficacy. [PDF]
ACS Pharmacol Transl Sci, 2022 Cui CS +5 more
europepmc +1 more source
Inflammatory Stewardship—A Perspective for Active Management of Acute Inflammation
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.Inflammatory stewardship frames inflammation as a manageable clinical domain requiring explicit strategy, governance, and feedback. It aligns diagnostics, risk stratification, biomarker interpretation, and immunomodulatory decisions across perioperative and critical‐care teams.
Lennart Finn Herrlich +2 more
wiley +1 more source
Stiffness-tuned and ROS-sensitive hydrogel incorporating complement C5a receptor antagonist modulates antibacterial activity of macrophages for periodontitis treatment. [PDF]
Bioact Mater, 2023 Gan Z +10 more
europepmc +1 more source
Mild Hypothermia Alleviates Complement C5a-Induced Neuronal Autophagy During Brain Ischemia-Reperfusion Injury After Cardiac Arrest. [PDF]
Cell Mol Neurobiol, 2023 Wang L +11 more
europepmc +1 more source
The role of complement C5a receptor in DPSC odontoblastic differentiation and in vivo reparative dentin formation. [PDF]
Int J Oral Sci, 2022 Irfan M +6 more
europepmc +1 more source