Results 151 to 160 of about 11,877 (255)

Self-Dimerization Induced Proximity Targeting Chimeras (SDIPTAC) Lead to DCAF1 Loss of Function and Inhibition of HIV Replication. [PDF]

J Med Chem
Mabanglo MF, Srivastava S, Matsui Y, Li Z, Noureldin M, Pogmore JP, Hoffer L, Taherian F, Hajian T, Tucker S, Mamai A, Kiyota T, Aman A, Al-Awar R, Marcellus R, Uehling DE, Ott M, Ramnauth J, Vedadi M.   +18 more
europepmc   +1 more source

A Single‐Nucleotide Substitution Generates a de Novo Promoter That Activates a Latent Metabolic Bypass in Escherichia coli

Molecular Microbiology, EarlyView.
A chromosomal mutation allows bypass of deletion of the Escherichia coli fabH gene. The bypass results from creation of a new promoter that drives increased madA transcription, resulting in increased synthesis of acetyl‐acyl carrier protein by decarboxylation of malonyl‐acyl carrier protein.
Qiaoqiao Guo, Qi Zou, Jilong Qin, Makrina Totsika, Yaoqin Hong, John E. Cronan   +5 more
wiley   +1 more source

Post-ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat. [PDF]

Physiol Rep
McGraw M, Sharma A, Bhattarai D, Joshi N, Gokden N, Lee SO, Venugopal G, Parajuli N.   +7 more
europepmc   +1 more source

Inference on Common Trends in a Cointegrated Nonlinear SVAR

Oxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT We consider the problem of performing inference on the number of common stochastic trends when data is generated by a cointegrated CKSVAR (a two‐regime, piecewise affine SVAR; Mavroeidis, 2021), using a modified version of the Breitung (2002) multivariate variance ratio test that is robust to the presence of nonlinear cointegration (of a known
James A. Duffy, Xiyu Jiao
wiley   +1 more source

Plasmatic Profiling of Individuals With Combinations of Type 2 Diabetes Mellitus, Dyslipidemia and Periodontitis: A Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Aim The objective of this study was to investigate the global profile of plasmatic proteins of individuals affected simultaneously or not by type 2 diabetes mellitus (T2DM, well/poorly‐controlled), Dyslipidemia (DL), and Periodontitis (P). Methods Besides periodontal examination, plasma was collected for glycemic, and lipid analyses from 150 ...
François Isnaldo Dias Caldeira, Sâmia Cruz Tfaile Corbi, Alliny de Souza Bastos, Silvana Regina Perez Orrico, Cristiane Ribeiro Salmon, Yizhi Xiao, Walter Luiz Siqueira, Raquel Mantuaneli Scarel‐Caminaga   +7 more
wiley   +1 more source

Predicting Chromatographic Retention Times from Quantum-Chemical Solvation Free Energies: A Pilot Study of Oxysterols. [PDF]

J Phys Chem A
Janesko BG, Li L.
europepmc   +1 more source

Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY–CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu, Lihua Zhu, Chenyu Shao, Siyi Xie, Na Li, Xinyu Li, Fang Wang, Lvwen Peng, Huiying Jin, Fanghuizi Shang, Jianan Huang, Zhonghua Liu, Na Tian, Shuoqian Liu   +13 more
wiley   +1 more source

Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis. [PDF]

Nat Commun
Röttgerding F, Reyer F, Gerlach E, Amborn M, Duschek N, Schultze TG, Fingerle V, Roome CM, Stumpf M, Becker K, Rahlfs S, Przyborski JM, Kraiczy P, Fritz-Wolf K.   +13 more
europepmc   +1 more source

Oxidative stress in honey bees (Apis mellifera) and small carpenter bees (Ceratina calcarata) across different landscapes

Physiological Entomology, EarlyView.
First comparative study in oxidative stress between wild bees and managed bees. Bees collected from organic landscapes exhibited the lowest OX levels. Pesticide profiles were different among landscapes. Abstract Oxidative stress (OX) is a state of imbalance between antioxidants and reactive oxygen species, which are the byproducts of oxidative ...
Keiana Briscoe, Mia Byarlay, Rameshwor Pudasaini, Reed Johnson, Sandra Rehan, Hongmei Li‐Byarlay   +5 more
wiley   +1 more source